Contributions of tidal lung inflation to human R–R interval and arterial pressure fluctuations

We studied the effects of mechanical lung inflation on respiratory frequency R–R interval and arterial pressure fluctuations in nine healthy young adults undergoing elective orthopedic surgery. We conducted this research to define the contribution of pulmonary and thoracic stretch receptor input to...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the autonomic nervous system 1998-01, Vol.68 (1), p.89-95
Main Authors: Koh, Junken, Brown, Troy E, Beightol, Larry A, Eckberg, Dwain L
Format: Article
Language:English
Subjects:
Adult
Algorithms
Arrhythmias, Cardiac - physiopathology
Arteries - physiology
Biological and medical sciences
Blood Pressure - physiology
Electric Stimulation
Electrocardiography
Female
Fentanyl
Fundamental and applied biological sciences. Psychology
Heart Rate - physiology
High frequency jet ventilation
Humans
Lung - physiology
Male
Peripheral nervous system. Autonomic nervous system. Neuromuscular transmission. Ganglionic transmission. Electric organ
Respiratory Mechanics - physiology
Respiratory sinus arrhythmia
Sedation
Space life sciences
Tidal Volume - physiology
Vecuronium
Vertebrates: nervous system and sense organs
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We studied the effects of mechanical lung inflation on respiratory frequency R–R interval and arterial pressure fluctuations in nine healthy young adults undergoing elective orthopedic surgery. We conducted this research to define the contribution of pulmonary and thoracic stretch receptor input to respiratory sinus arrhythmia. We compared fast Fourier transform spectral power during three modes of ventilation: (1) spontaneous, frequency-controlled (0.25 Hz) breathing, (2) intermittent positive pressure ventilation (0.25 Hz, with a tidal volume of 8 ml/kg) and (3) high frequency jet ventilation (5.0 Hz, 2.5 kg/cm 2), after sedation and vecuronium paralysis. Mean R–R intervals, arterial pressures and arterial blood gas levels were comparable during all three breathing conditions. Respiratory frequency systolic pressure spectral power was comparable during spontaneous breathing and conventional mechanical ventilation, but was significantly reduced during high frequency jet ventilation ( P
ISSN:0165-1838
1872-7476
DOI:10.1016/S0165-1838(97)00114-8