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Acetamidine Lysine Derivative, N-(5(S)-amino-6,7-dihydroxyheptyl)ethanimidamide Dihydrochloride: A Highly Selective Inhibitor of Human Inducible Nitric Oxide Synthase

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Bibliographic Details
Published in:	Journal of medicinal chemistry 1998-03, Vol.41 (6), p.775-777
Main Authors:	Hallinan, E. Ann, Tsymbalov, Sofya, Finnegan, Patricia M, Moore, William M, Jerome, Gina M, Currie, Mark G, Pitzele, Barnett S
Format:	Article
Language:	English
Subjects:	Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Enzyme Induction - drug effects Enzyme Inhibitors - chemical synthesis Enzyme Inhibitors - chemistry Enzyme Inhibitors - pharmacology Fatty Alcohols - chemical synthesis Fatty Alcohols - chemistry Fatty Alcohols - pharmacology Humans Imines - chemical synthesis Imines - chemistry Imines - pharmacology Magnetic Resonance Spectroscopy Medical sciences Nitric Oxide Synthase - antagonists & inhibitors Nitric Oxide Synthase - biosynthesis Nitric Oxide Synthase Type II Pharmacology. Drug treatments Stereoisomerism Structure-Activity Relationship
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