Identification of rhodopsin in the pigeon deep brain

We detected rhodopsin gene expression in the pigeon lateral septum, a photosensitive deep brain region that is responsible for the photoperiodic gonadal response. The nucleotide sequence of the deep brain rhodopsin cDNA clone exactly matched that of the retinal one, indicating that a single rhodopsi...

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Bibliographic Details
Published in:FEBS letters 1998-03, Vol.424 (1), p.53-56
Main Authors: Wada, Yasutaka, Okano, Toshiyuki, Adachi, Akihito, Ebihara, Shizufumi, Fukada, Yoshitaka
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Animals
Brain Chemistry
Cerebrospinal fluid-contacting neuron
Columbidae
CSF, cerebrospinal fluid
Deep brain photoreceptor
Lateral septum
Molecular Sequence Data
Neurons - metabolism
PCR, polymerase chain reaction
Photoperiodic response
Pigeon
RACE, rapid amplification of cDNA ends
Retina - cytology
Retina - metabolism
Rhodopsin
Rhodopsin - analysis
Rhodopsin - genetics
RT-PCR, reverse transcription-polymerase chain reaction
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Summary:We detected rhodopsin gene expression in the pigeon lateral septum, a photosensitive deep brain region that is responsible for the photoperiodic gonadal response. The nucleotide sequence of the deep brain rhodopsin cDNA clone exactly matched that of the retinal one, indicating that a single rhodopsin gene is transcribed in the two tissues. Immunohistochemical analysis localized rhodopsin in the cerebrospinal fluid-contacting neurons, which have been assumed to be photoreceptive cells in the deep brain. Pigeon rhodopsin seems to play dual important roles in the visual and non-visual systems, the latter of which contributes to the photoperiodic response.
ISSN:0014-5793
1873-3468
DOI:10.1016/S0014-5793(98)00138-0