Circulating met-enkephalin in trained athletes during rest, exhaustive treadmill exercise and marathon running

Twelve trained male athletes were subjected to a progressive intensity treadmill exercise test to total exhaustion and at a later date took part in the Comrades Marathon. Blood was taken in order to determine whether plasma met-enkephalin levels increase in an exercise-intensity dependent manner. Th...

Full description

Saved in:
Bibliographic Details
Published in:European journal of clinical pharmacology 1990-01, Vol.38 (4), p.391-392
Main Authors: SOMMERS, D. K, LOOTS, J. M, SIMPSON, S. F, MEYER, E. C, DETTWEILER, A, HUMAN, J. R
Format: Article
Language:English
Subjects:
Adult
Applied physiology
Biological and medical sciences
Enkephalin, Methionine - blood
Human physiology applied to population studies and life conditions. Human ecophysiology
Humans
Male
Medical sciences
Physical Exertion - physiology
Running
Time Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Twelve trained male athletes were subjected to a progressive intensity treadmill exercise test to total exhaustion and at a later date took part in the Comrades Marathon. Blood was taken in order to determine whether plasma met-enkephalin levels increase in an exercise-intensity dependent manner. The mean concentrations in f mol/ml were as follows: post-exercise levels (266) were significantly higher than basal levels (172), and the post-marathon levels (378) rose significantly above the post-exercise levels. The magnitude of the responses is thus correlated with the amount of work performed and would suggest that this opioid peptide is involved in physiological actions that perhaps extend beyond the pharmacological actions of opiate drugs.
ISSN:0031-6970
1432-1041
DOI:10.1007/BF00315582