Coagulase-negative staphylococci in a major Danish university hospital: diversity in antibiotic susceptibility between wards

Over a one‐year period, all coagulase‐negative staphylococci (CoNS) from blood cultures, cerebrospinal fluids and peritoneal effluents from patients in a major Danish university hospital were investigated for susceptibility to penicillin G; methicillin; gentamicin; netilmicin; amikacin; erythromycin...

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Published in:APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 1998-03, Vol.106 (1-6), p.411-416
Main Authors: Jarloev, JO, Hoeiby, N
Format: Article
Language:English
Subjects:
Antibacterial agents
antibiotic susceptibility
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Coagulase - analysis
Coagulase-negative staphylococci
different wards
diversity
Drug Resistance, Microbial
Female
Hospitals, University
Humans
Male
Medical sciences
Microbial Sensitivity Tests
Pharmacology. Drug treatments
Staphylococcus
Staphylococcus - drug effects
Staphylococcus - enzymology
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Summary:Over a one‐year period, all coagulase‐negative staphylococci (CoNS) from blood cultures, cerebrospinal fluids and peritoneal effluents from patients in a major Danish university hospital were investigated for susceptibility to penicillin G; methicillin; gentamicin; netilmicin; amikacin; erythromycin; clindamycin; fusidic acid; rifampicin; tetracycline; chloramphenicol; ciprofloxacin; teicoplanin; and vancomycin. Among the CoNS‐isolates, 56% were resistant to methicillin, 51% to gentamicin, 28% to ciprofloxacin, and 5% to teicoplanin. Blood culture CoNS‐isolates from patients with a central venous catheter (CVC) were more often resistant to various antibiotics compared to CoNS‐isolates from patients without a CVC, e.g. methicillin (72%vs 21%), gentamicin (65%vs 22%) (p
ISSN:0903-4641
1600-0463
DOI:10.1111/j.1699-0463.1998.tb01365.x