Successful Treatment of Trichosporon beigelii Pneumonia with Itraconazole

Among patients with neoplastic diseases who are undergoing myeloablation, a growing number of uncommon fungal pathogens (including Trichosporon beigelii) have been reported to cause infection. Amphotericin B has limited activity against T. beigelii. On the basis of in vitro studies, some authors hav...

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Bibliographic Details
Published in:Clinical infectious diseases 1998-04, Vol.26 (4), p.999-1000
Main Authors: Canales, Miguel Angel, Sevilla, Julián, Gutierrez, Emilio Ojeda, Navarro, Fernando Hernández
Format: Article
Language:English
Subjects:
Adult
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal agents
Antifungal Agents - therapeutic use
Azoles
Biological and medical sciences
Brief Reports
Female
Fever
Fungal infections
Humans
Infections
Itraconazole - therapeutic use
Medical sciences
Mycoses - diagnostic imaging
Mycoses - drug therapy
Pathogens
Pharmacology. Drug treatments
Pneumonia
Pneumonia - diagnostic imaging
Pneumonia - drug therapy
Pneumonia - microbiology
Sputum
Tomography, X-Ray Computed
triazoles
Trichosporon
Trichosporon beigelii
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Summary:Among patients with neoplastic diseases who are undergoing myeloablation, a growing number of uncommon fungal pathogens (including Trichosporon beigelii) have been reported to cause infection. Amphotericin B has limited activity against T. beigelii. On the basis of in vitro studies, some authors have suggested treatment with triazole compounds. We describe a patient with T. beigelii pneumonia whose condition responded to therapy with itraconazole.
ISSN:1058-4838
1537-6591
DOI:10.1086/517648