The postprandial portal flow is related to the severity of portal hypertension and liver cirrhosis

Background/Aims: Diminished postprandial portal hyperemia has been demonstrated by echo-Doppler flowmetry in patients with liver cirrhosis, but its diagnostic role is unclear. This prospective study was therefore undertaken in patients with varying severity of portal hypertension and degree of liver...

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Bibliographic Details
Published in:Journal of hepatology 1998-04, Vol.28 (4), p.631-638
Main Authors: Ludwig, Diether, Schwarting, Karsten, Korbel, Cornelia M., Brüning, Andreas, Schiefer, Bernhard, Stange, Eduard F.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Blood Flow Velocity
Case-Control Studies
Duplex Doppler sonography
Esophageal and Gastric Varices - physiopathology
Esophageal varices
Female
Gastroenterology. Liver. Pancreas. Abdomen
Hemodynamics - physiology
Humans
Hypertension, Portal - diagnostic imaging
Hypertension, Portal - physiopathology
Liver cirrhosis
Liver Cirrhosis - physiopathology
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Middle Aged
Other diseases. Semiology
Portal hypertension
Portal hypertensive gastropathy
Portal System - physiology
Postprandial hyperemia
Postprandial Period
Prospective Studies
Reference Values
Ultrasonography, Doppler, Duplex
Variceal bleeding
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Summary:Background/Aims: Diminished postprandial portal hyperemia has been demonstrated by echo-Doppler flowmetry in patients with liver cirrhosis, but its diagnostic role is unclear. This prospective study was therefore undertaken in patients with varying severity of portal hypertension and degree of liver cirrhosis. Methods: Portal flowmetry was performed in 66 patients with cirrhosis and 20 healthy volunteers during fasting and 30 min after ingestion of a standardized meal. Hemodynamic parameters were related to the degree of esophageal varices, variceal bleeding, portal hypertensive gastropathy and Child-Pugh score. Results: The postprandial portal blood velocity increment was low in patients with esophageal varices of any degree (22–24%), compared to patients without varices (49%, p
ISSN:0168-8278
1600-0641
DOI:10.1016/S0168-8278(98)80287-0