SENSITIVITY OF CARBOHYDRATE-DEFICIENT TRANSFERRIN (CDT) IN RELATION TO AGE AND DURATION OF ABSTINENCE

Carbohydrate-deficient transferrin (CDT) serum concentrations were prospectively determined in 162 subjects (alcoholics n = 62, controls n=100) using three different methods of detection (IEF, CDTectTM, Axis%CDTTM). Repeated testing in alcoholics after 3 and 5 days of abstinence demonstrated a signi...

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Bibliographic Details
Published in:Alcohol and alcoholism (Oxford) 1998-03, Vol.33 (2), p.164-167
Main Authors: AGELINK, M. W., DIRKES-KERSTING, A., ZEIT, T., BERTLING, R., MALESSA, R., KLIESER, E.
Format: Article
Language:English
Subjects:
Adult
Aged
Aging - metabolism
Alcohol Drinking - blood
Alcoholism and acute alcohol poisoning
Biological and medical sciences
Biomarkers
Female
Humans
Male
Medical sciences
Middle Aged
Prospective Studies
Psychiatric Status Rating Scales
Temperance
Time Factors
Toxicology
Transferrin - analogs & derivatives
Transferrin - metabolism
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Summary:Carbohydrate-deficient transferrin (CDT) serum concentrations were prospectively determined in 162 subjects (alcoholics n = 62, controls n=100) using three different methods of detection (IEF, CDTectTM, Axis%CDTTM). Repeated testing in alcoholics after 3 and 5 days of abstinence demonstrated a significantly higher sensitivity of CDT in patients above 40 years of age compared to younger patients.
ISSN:0735-0414
1464-3502
DOI:10.1093/oxfordjournals.alcalc.a008373