Low Serum Thyroxine on Initial Newborn Screening Is Associated With Intraventricular Hemorrhage and Death in Very Low Birth Weight Infants

Transient hypothyroxinemia (TH) of prematurity has been correlated with poor neurodevelopmental outcome. However, the relationship between thyroid function and neonatal mortality and brain injury has not been described. To investigate the relationship between thyroid function and neonatal outcome. R...

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Bibliographic Details
Published in:Pediatrics (Evanston) 1998-05, Vol.101 (5), p.903-907
Main Authors: Paul, David A, Leef, Kathleen H, Stefano, John L, Bartoshesky, Louis
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Babies
Biological and medical sciences
Birth weight, Low
Brain
Brain hemorrhage
Cerebral Hemorrhage - epidemiology
Emergency and intensive care: neonates and children. Prematurity. Sudden death
Health aspects
Hemorrhage
Hormones
Hospital Mortality
Humans
Hypothyroidism
Infant Mortality
Infant, Newborn
Infant, Premature - blood
Infant, Very Low Birth Weight - blood
Infants (Premature)
Intensive care medicine
Leukomalacia, Periventricular - epidemiology
Low birth weight
Medical sciences
Medical screening
Mortality
Multivariate Analysis
Neonatal Screening
Odds Ratio
Patient outcomes
Pediatrics
Physiological aspects
Premature infants
Risk Factors
Thyrotropin - blood
Thyroxine
Thyroxine - blood
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Summary:Transient hypothyroxinemia (TH) of prematurity has been correlated with poor neurodevelopmental outcome. However, the relationship between thyroid function and neonatal mortality and brain injury has not been described. To investigate the relationship between thyroid function and neonatal outcome. Review of infants weighing
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.101.5.903