Endocrine changes in women conceiving during treatment with an LHRH agonist

We report on eight patients who conceived during pituitary desensitization with buserelin in the Meal phase of the menstrual cycle. Pregnancy was diagnosed between day 12 and 21 of buserelin administration. Analysis of serum luteinizing hormone on day 12 showed that pituitary desensitization occurre...

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Bibliographic Details
Published in:Human reproduction (Oxford) 1990-05, Vol.5 (4), p.409-412
Main Authors: Isherwood, P.J., Ibrahim, Z.H.Z., Matson, P.L., Morroll, D.R., Burslem, R.W., Lieberman, B.A.
Format: Article
Language:English
Subjects:
Adult
buserelin
Buserelin - pharmacology
Chorionic Gonadotropin - blood
Down-Regulation
early pregnancy
Estradiol - blood
Female
Humans
LHRH agonist
Luteal Phase
Luteinizing Hormone - blood
Pituitary Gland - drug effects
Pregnancy - blood
Pregnancy - physiology
Progesterone - blood
Retrospective Studies
Citations: Items that cite this one
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Summary:We report on eight patients who conceived during pituitary desensitization with buserelin in the Meal phase of the menstrual cycle. Pregnancy was diagnosed between day 12 and 21 of buserelin administration. Analysis of serum luteinizing hormone on day 12 showed that pituitary desensitization occurred in conjunction with increasing production of ovarian steroid hormones. Serum concentrations of human chorionic gonadotrophin (HCG) were
ISSN:0268-1161
1460-2350
DOI:10.1093/oxfordjournals.humrep.a137112