Metastatic rhabdomyosarcoma presenting as intracranial hemorrhage: imaging findings

The CNS is rarely the first site of metastasis for rhabdomyosarcoma. CNS involvement is uncommon, and usually seen as leptomeningeal spread after development of pulmonary metastases. We present the imaging findings in a 13-year-old boy in whom a large intracranial hemorrhage was the initial presenta...

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Bibliographic Details
Published in:European journal of radiology 1998-02, Vol.26 (3), p.241-243
Main Authors: Ahola, David T, Provenzale, James M, Longee, Darryl C
Format: Article
Language:English
Subjects:
Biological and medical sciences
Brain
Brain Neoplasms - complications
Brain Neoplasms - diagnosis
Brain Neoplasms - secondary
Cerebral Hemorrhage - diagnosis
Cerebral Hemorrhage - etiology
Child
Drug therapy
Hemodynamics
Hemorrhage
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Metastasis
Neurology
Neurophysiology
Prostatic Neoplasms - pathology
Pulmonary diseases
Rhabdomyosarcoma
Rhabdomyosarcoma, Embryonal - complications
Rhabdomyosarcoma, Embryonal - diagnosis
Rhabdomyosarcoma, Embryonal - secondary
Tomography, X-Ray Computed
Tumors of the nervous system. Phacomatoses
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Summary:The CNS is rarely the first site of metastasis for rhabdomyosarcoma. CNS involvement is uncommon, and usually seen as leptomeningeal spread after development of pulmonary metastases. We present the imaging findings in a 13-year-old boy in whom a large intracranial hemorrhage was the initial presentation of surgically documented metastatic prostatic rhabdomyosarcoma. Multiple chest CTs and radionuclide bone scans had previously shown no evidence of pulmonary or osseous metastases. The significance of this case in relation to the possible role of the need for use of chemotherapeutic agents that cross the blood-brain barriers to prevent brain metastasis is discussed.
ISSN:0720-048X
1872-7727
DOI:10.1016/S0720-048X(97)00030-2