Loading…

Analysis of Rickettsia tsutsugamushi Amplified DNA That Encodes an Antigenic Gene Product

Scrub typhus is found throughout parts of Asia, Australia, and the Pacific Islands. The disease is clustered geographically, probably because of the suitability of local habitats for the appropriate rodent host and the disease vector, the trombiculid mite. Rickettsia tsutsugamushi is the causative a...

Full description

Saved in:

Bibliographic Details
Published in:	Annals of the New York Academy of Sciences 1990-01, Vol.590 (1), p.483-484
Main Authors:	SPRUILL, C. L., REGNERY, R. L.
Format:	Article
Language:	English
Subjects:	antigens Antigens, Bacterial - genetics Bacteriology Biological and medical sciences DNA DNA, Bacterial - analysis Fundamental and applied biological sciences. Psychology Gene Amplification Genetics Microbiology Orientia tsutsugamushi - genetics
Citations:	Items that cite this one
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

cited_by	cdi_FETCH-LOGICAL-c4693-d37420e39f24425ff4b07b6a6892c58f36a20ea5d559d7c3edda3939d2712f043
cites
container_end_page	484
container_issue	1
container_start_page	483
container_title	Annals of the New York Academy of Sciences
container_volume	590
creator	SPRUILL, C. L. REGNERY, R. L.
description	Scrub typhus is found throughout parts of Asia, Australia, and the Pacific Islands. The disease is clustered geographically, probably because of the suitability of local habitats for the appropriate rodent host and the disease vector, the trombiculid mite. Rickettsia tsutsugamushi is the causative agent of the disease, which is confirmed by serologic tests. Isolates of this species show a good deal of antigenic variation. To provide a relatively simple method of isolate identification and to better understand the genetic relatedness between isolates, we have studied the DNA that encodes an important antigen present during scrub typhus infections, using gene amplification techniques and restriction fragment length polymorphism (RFLP) analysis. This paper is a preliminary communication of that work; a manuscript describing these studies in more detail is in preparation.
doi_str_mv	10.1111/j.1749-6632.1990.tb42257.x
format	article
fullrecord	<record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79916196</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>16014556</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4693-d37420e39f24425ff4b07b6a6892c58f36a20ea5d559d7c3edda3939d2712f043</originalsourceid><addsrcrecordid>eNqVUctuEzEUHSFQCYVPQLKQYDeD347ZoKG0KSgKFRRFXVmOH63TeYTxjEj-Ho8yCkvElaW7OOeee31Olr1BsECp3m8LJKjMOSe4QFLCot9QjJko9k-y2Ql6ms0gFCKfS0yeZy9i3EKI8JyKs-wMI8QRgrPsrmx0dYghgtaD78E8ur6PQYM-Dund63qIDwGU9a4KPjgLPq9KcPuge3DZmNa6CHQDyqYP964JBixc48BN19rB9C-zZ15X0b2a-nn28-ry9uI6X35bfLkol7mhXJLcEkExdER6TClm3tMNFBuueTrbsLknXCdYM8uYtMIQZ60mkkiLBcIeUnKevTvq7rr21-Bir-oQjasq3bh2iEpImf4q-T-JiENEGRuJH45E07Uxds6rXRdq3R0UgmoMQG3V6LIaXVZjAGoKQO3T8Otpy7CpnT2NTo4n_O2E62h05TvdmBD_bpAMJj9E4n088n6Hyh3-4wK1uit_0DlJCvlRIcTe7U8KuntUXBDB1Hq1UFc3X9ef1strhcgfEjuxSQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>16014556</pqid></control><display><type>article</type><title>Analysis of Rickettsia tsutsugamushi Amplified DNA That Encodes an Antigenic Gene Product</title><source>Wiley Online (Archive)</source><creator>SPRUILL, C. L. ; REGNERY, R. L.</creator><contributor>Paretsky, D ; Mallavia, LP (eds) ; Hechemy, KE ; Walker, DH</contributor><creatorcontrib>SPRUILL, C. L. ; REGNERY, R. L. ; Paretsky, D ; Mallavia, LP (eds) ; Hechemy, KE ; Walker, DH</creatorcontrib><description>Scrub typhus is found throughout parts of Asia, Australia, and the Pacific Islands. The disease is clustered geographically, probably because of the suitability of local habitats for the appropriate rodent host and the disease vector, the trombiculid mite. Rickettsia tsutsugamushi is the causative agent of the disease, which is confirmed by serologic tests. Isolates of this species show a good deal of antigenic variation. To provide a relatively simple method of isolate identification and to better understand the genetic relatedness between isolates, we have studied the DNA that encodes an important antigen present during scrub typhus infections, using gene amplification techniques and restriction fragment length polymorphism (RFLP) analysis. This paper is a preliminary communication of that work; a manuscript describing these studies in more detail is in preparation.</description><identifier>ISSN: 0077-8923</identifier><identifier>EISSN: 1749-6632</identifier><identifier>DOI: 10.1111/j.1749-6632.1990.tb42257.x</identifier><identifier>PMID: 2116110</identifier><identifier>CODEN: ANYAA9</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>antigens ; Antigens, Bacterial - genetics ; Bacteriology ; Biological and medical sciences ; DNA ; DNA, Bacterial - analysis ; Fundamental and applied biological sciences. Psychology ; Gene Amplification ; Genetics ; Microbiology ; Orientia tsutsugamushi - genetics</subject><ispartof>Annals of the New York Academy of Sciences, 1990-01, Vol.590 (1), p.483-484</ispartof><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4693-d37420e39f24425ff4b07b6a6892c58f36a20ea5d559d7c3edda3939d2712f043</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1749-6632.1990.tb42257.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1749-6632.1990.tb42257.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>309,310,314,780,784,789,790,1416,23930,23931,25140,27924,27925,46049,46473</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19504207$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2116110$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Paretsky, D</contributor><contributor>Mallavia, LP (eds)</contributor><contributor>Hechemy, KE</contributor><contributor>Walker, DH</contributor><creatorcontrib>SPRUILL, C. L.</creatorcontrib><creatorcontrib>REGNERY, R. L.</creatorcontrib><title>Analysis of Rickettsia tsutsugamushi Amplified DNA That Encodes an Antigenic Gene Product</title><title>Annals of the New York Academy of Sciences</title><addtitle>Ann N Y Acad Sci</addtitle><description>Scrub typhus is found throughout parts of Asia, Australia, and the Pacific Islands. The disease is clustered geographically, probably because of the suitability of local habitats for the appropriate rodent host and the disease vector, the trombiculid mite. Rickettsia tsutsugamushi is the causative agent of the disease, which is confirmed by serologic tests. Isolates of this species show a good deal of antigenic variation. To provide a relatively simple method of isolate identification and to better understand the genetic relatedness between isolates, we have studied the DNA that encodes an important antigen present during scrub typhus infections, using gene amplification techniques and restriction fragment length polymorphism (RFLP) analysis. This paper is a preliminary communication of that work; a manuscript describing these studies in more detail is in preparation.</description><subject>antigens</subject><subject>Antigens, Bacterial - genetics</subject><subject>Bacteriology</subject><subject>Biological and medical sciences</subject><subject>DNA</subject><subject>DNA, Bacterial - analysis</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gene Amplification</subject><subject>Genetics</subject><subject>Microbiology</subject><subject>Orientia tsutsugamushi - genetics</subject><issn>0077-8923</issn><issn>1749-6632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><recordid>eNqVUctuEzEUHSFQCYVPQLKQYDeD347ZoKG0KSgKFRRFXVmOH63TeYTxjEj-Ho8yCkvElaW7OOeee31Olr1BsECp3m8LJKjMOSe4QFLCot9QjJko9k-y2Ql6ms0gFCKfS0yeZy9i3EKI8JyKs-wMI8QRgrPsrmx0dYghgtaD78E8ur6PQYM-Dund63qIDwGU9a4KPjgLPq9KcPuge3DZmNa6CHQDyqYP964JBixc48BN19rB9C-zZ15X0b2a-nn28-ry9uI6X35bfLkol7mhXJLcEkExdER6TClm3tMNFBuueTrbsLknXCdYM8uYtMIQZ60mkkiLBcIeUnKevTvq7rr21-Bir-oQjasq3bh2iEpImf4q-T-JiENEGRuJH45E07Uxds6rXRdq3R0UgmoMQG3V6LIaXVZjAGoKQO3T8Otpy7CpnT2NTo4n_O2E62h05TvdmBD_bpAMJj9E4n088n6Hyh3-4wK1uit_0DlJCvlRIcTe7U8KuntUXBDB1Hq1UFc3X9ef1strhcgfEjuxSQ</recordid><startdate>19900101</startdate><enddate>19900101</enddate><creator>SPRUILL, C. L.</creator><creator>REGNERY, R. L.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QO</scope><scope>7T5</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>19900101</creationdate><title>Analysis of Rickettsia tsutsugamushi Amplified DNA That Encodes an Antigenic Gene Product</title><author>SPRUILL, C. L. ; REGNERY, R. L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4693-d37420e39f24425ff4b07b6a6892c58f36a20ea5d559d7c3edda3939d2712f043</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>antigens</topic><topic>Antigens, Bacterial - genetics</topic><topic>Bacteriology</topic><topic>Biological and medical sciences</topic><topic>DNA</topic><topic>DNA, Bacterial - analysis</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gene Amplification</topic><topic>Genetics</topic><topic>Microbiology</topic><topic>Orientia tsutsugamushi - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SPRUILL, C. L.</creatorcontrib><creatorcontrib>REGNERY, R. L.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Immunology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of the New York Academy of Sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SPRUILL, C. L.</au><au>REGNERY, R. L.</au><au>Paretsky, D</au><au>Mallavia, LP (eds)</au><au>Hechemy, KE</au><au>Walker, DH</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Analysis of Rickettsia tsutsugamushi Amplified DNA That Encodes an Antigenic Gene Product</atitle><jtitle>Annals of the New York Academy of Sciences</jtitle><addtitle>Ann N Y Acad Sci</addtitle><date>1990-01-01</date><risdate>1990</risdate><volume>590</volume><issue>1</issue><spage>483</spage><epage>484</epage><pages>483-484</pages><issn>0077-8923</issn><eissn>1749-6632</eissn><coden>ANYAA9</coden><abstract>Scrub typhus is found throughout parts of Asia, Australia, and the Pacific Islands. The disease is clustered geographically, probably because of the suitability of local habitats for the appropriate rodent host and the disease vector, the trombiculid mite. Rickettsia tsutsugamushi is the causative agent of the disease, which is confirmed by serologic tests. Isolates of this species show a good deal of antigenic variation. To provide a relatively simple method of isolate identification and to better understand the genetic relatedness between isolates, we have studied the DNA that encodes an important antigen present during scrub typhus infections, using gene amplification techniques and restriction fragment length polymorphism (RFLP) analysis. This paper is a preliminary communication of that work; a manuscript describing these studies in more detail is in preparation.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>2116110</pmid><doi>10.1111/j.1749-6632.1990.tb42257.x</doi><tpages>2</tpages></addata></record>
fulltext	fulltext
identifier	ISSN: 0077-8923
ispartof	Annals of the New York Academy of Sciences, 1990-01, Vol.590 (1), p.483-484
issn	0077-8923 1749-6632
language	eng
recordid	cdi_proquest_miscellaneous_79916196
source	Wiley Online (Archive)
subjects	antigens Antigens, Bacterial - genetics Bacteriology Biological and medical sciences DNA DNA, Bacterial - analysis Fundamental and applied biological sciences. Psychology Gene Amplification Genetics Microbiology Orientia tsutsugamushi - genetics
title	Analysis of Rickettsia tsutsugamushi Amplified DNA That Encodes an Antigenic Gene Product
url	http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T20%3A08%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Analysis%20of%20Rickettsia%20tsutsugamushi%20Amplified%20DNA%20That%20Encodes%20an%20Antigenic%20Gene%20Product&rft.jtitle=Annals%20of%20the%20New%20York%20Academy%20of%20Sciences&rft.au=SPRUILL,%20C.%20L.&rft.date=1990-01-01&rft.volume=590&rft.issue=1&rft.spage=483&rft.epage=484&rft.pages=483-484&rft.issn=0077-8923&rft.eissn=1749-6632&rft.coden=ANYAA9&rft_id=info:doi/10.1111/j.1749-6632.1990.tb42257.x&rft_dat=%3Cproquest_cross%3E16014556%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c4693-d37420e39f24425ff4b07b6a6892c58f36a20ea5d559d7c3edda3939d2712f043%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=16014556&rft_id=info:pmid/2116110&rfr_iscdi=true