Optimizing screening procedures for Staphylococcus aureus nasal carriage in patients on haemodialysis

So far it remains unclear what the optimal screening method for detection of S. aureus nasal carriage in patients on haemodialysis is with regard to number of cultures performed, culture interval, and necessity of a broth-enrichment procedure. A prospective, uncontrolled study was performed at the r...

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Bibliographic Details
Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 1998-05, Vol.13 (5), p.1256-1258
Main Authors: WANTEN, G. J. A, SCHNEEBERGER, P. M, BEVERS, A, VAN GINNEKEN, E, KOOLEN, M. I
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Carrier State - microbiology
Emergency and intensive care: renal failure. Dialysis management
Female
Humans
Intensive care medicine
Male
Mass Screening - methods
Medical sciences
Microbiological Techniques
Nasal Cavity - microbiology
Prospective Studies
Renal Dialysis
Staphylococcus aureus - isolation & purification
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Summary:So far it remains unclear what the optimal screening method for detection of S. aureus nasal carriage in patients on haemodialysis is with regard to number of cultures performed, culture interval, and necessity of a broth-enrichment procedure. A prospective, uncontrolled study was performed at the renal unit of a tertiary care centre, including all haemodialysis patients (n=91) attending the unit during the study period. The purpose was to determine the optimal screening method for S. aureus nasal carriage in patients on haemodialysis. When compared to the conventional culture method, inclusion of a broth-enrichment procedure increased the number of cultures positive for S. aureus significantly (31 vs 24%, P24-h) sampling procedure showed no significantly different results. S. aureus nasal carriage in haemodialysis patients can be conveniently established with three nasal cultures taken with 1-h intervals, and the inclusion of a broth-enrichment procedure.
ISSN:0931-0509
1460-2385
1460-2385
DOI:10.1093/ndt/13.5.1256