A controlled trial of the effects of pattern of alcohol intake on serum lipid levels in regular drinkers

To determine whether the effects of drinking pattern (predominantly weekend versus daily drinking) have differential effects on serum lipids, 55 healthy male drinkers were recruited on the basis of a regular alcohol intake, 210–500 ml absolute alcohol/week (≈3–6 standard drinks/day), with more than...

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Bibliographic Details
Published in:Atherosclerosis 1998-04, Vol.137 (2), p.243-252
Main Authors: Rakic, Valentina, Puddey, Ian B, Dimmitt, Simon B, Burke, Valerie, Beilin, Lawrence J
Format: Article
Language:English
Subjects:
Adult
Aged
Alcohol
Alcohol Drinking - blood
Alcoholism and acute alcohol poisoning
Apolipoprotein A-I - blood
Apolipoprotein A-I - drug effects
Apolipoprotein A-II - blood
Apolipoprotein A-II - drug effects
Biological and medical sciences
Cholesterol - blood
Cholesterol, HDL - blood
Cholesterol, HDL - drug effects
Cholesterol, LDL - blood
Cholesterol, LDL - drug effects
Daily drinking
Drinking pattern
Ethanol - administration & dosage
Humans
Life Style
Lipids
Lipids - blood
Lipoprotein(a) - blood
Lipoprotein(a) - drug effects
Lipoproteins
Male
Medical sciences
Middle Aged
Surveys and Questionnaires
Toxicology
Triglycerides - blood
Weekend drinking
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Summary:To determine whether the effects of drinking pattern (predominantly weekend versus daily drinking) have differential effects on serum lipids, 55 healthy male drinkers were recruited on the basis of a regular alcohol intake, 210–500 ml absolute alcohol/week (≈3–6 standard drinks/day), with more than 60% consumed as beer. Fourteen subjects were categorised as predominantly weekend drinkers, while 41 subjects regularly drank on a daily basis. After maintenance of their drinking pattern during a 4-week familiarisation, subjects were randomised to either consume low alcohol beer (0.9%, v/v) only, or to maintain their usual drinking habit consuming full-strength beer (5%, v/v) for the next 4 weeks. They then switched to full-strength or low alcohol beer, respectively, for a further 4 weeks. Their drinking pattern remained constant during the study. In both weekend and daily drinkers, a reduction in alcohol intake (i.e. from 387 ml/week to 88 ml/week for weekend drinkers and from 418 ml/week to 95 ml/week for daily drinkers, respectively, P
ISSN:0021-9150
1879-1484
DOI:10.1016/S0021-9150(97)00269-4