Effect of vitamin E on antioxidant enzymes and nitric oxide in ischemia-reperfused kidney injury

The effects of Vitamin E administration on antioxidant enzyme activities and nitrite‐nitrate levels of the reperfused rat kidney tissues were investigated by performing a 60 min ischemia followed by 24 and 72 hours of reperfusion. Vitamin E administration or the placebo (SF) was applied as 100 mg/kg...

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Bibliographic Details
Published in:Biochemistry and molecular biology international 1998-05, Vol.44 (6), p.1255-1263
Main Authors: Uysal, F, Girgin, F.K, Tuzun, S, Aldemir, S, Sozmen, E.Y
Format: Article
Language:English
Subjects:
Animals
antioxidants
Antioxidants - metabolism
Catalase - drug effects
Catalase - metabolism
free radicals
Kidney - blood supply
Kidney - metabolism
lipid peroxidation
Male
Malondialdehyde - metabolism
Nitric Oxide - metabolism
oxygen
protection
Rats
Reperfusion Injury - drug therapy
Reperfusion Injury - enzymology
Reperfusion Injury - metabolism
Superoxide Dismutase - drug effects
Superoxide Dismutase - metabolism
Thiobarbituric Acid Reactive Substances - metabolism
vitamin E
Vitamin E - pharmacology
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Summary:The effects of Vitamin E administration on antioxidant enzyme activities and nitrite‐nitrate levels of the reperfused rat kidney tissues were investigated by performing a 60 min ischemia followed by 24 and 72 hours of reperfusion. Vitamin E administration or the placebo (SF) was applied as 100 mg/kg BW. As expected, catalase (CAT) (p
ISSN:1039-9712
1521-6543
1521-6551
DOI:10.1080/15216549800202352