Testicular Microlithiasis with Mediastinal Choriocarcinoma: A Case Report

A 19‐year‐old Japanese male developed a cough, chest pain, and high fever. CT of the chest revealed a bulky mediastinal tumor (13 times 1O × 8 cm) and bilateral multiple pulmonary nodules. CT of the abdomen and pelvis was normal. Laboratory evaluation showed a beta human chorionic gonadotropin (βHCG...

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Bibliographic Details
Published in:International journal of urology 1998-05, Vol.5 (3), p.301-302
Main Authors: Nishiyama, Tsutomu, Terunuma, Masahiro, Iwashima, Akira, Souma, Takahiro, Hirahara, Hiroyuki
Format: Article
Language:English
Subjects:
Adult
Calcinosis - complications
Calcinosis - diagnostic imaging
choriocarcinoma
Choriocarcinoma - complications
Choriocarcinoma - diagnostic imaging
Choriocarcinoma - therapy
Chorionic Gonadotropin, beta Subunit, Human - blood
Combined Modality Therapy
Humans
Lung Diseases - complications
Male
Mediastinal Neoplasms - complications
Mediastinal Neoplasms - diagnostic imaging
Mediastinal Neoplasms - therapy
mediastinum
Radiography, Thoracic
Testicular Diseases - complications
Testicular Diseases - diagnostic imaging
testicular microlithiasis
Tomography, X-Ray Computed
Ultrasonography
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Summary:A 19‐year‐old Japanese male developed a cough, chest pain, and high fever. CT of the chest revealed a bulky mediastinal tumor (13 times 1O × 8 cm) and bilateral multiple pulmonary nodules. CT of the abdomen and pelvis was normal. Laboratory evaluation showed a beta human chorionic gonadotropin (βHCG) level of 985 ng/mL. Testicular ultrasonography demonstrated multiple, bilateral punctate echoes characteristic of testicular microlithiasis (TM). No primary testicular tumor was detected. Needle biopsies of the testes did not reveal cancer and calcification. Transthoracic needle biopsy of the mediastinal tumor showed choriocarcinoma. No correlation is known between TM and choriocarcinoma without testicular cancer, but the incidence of TM in this patient may reflect his high human chorionic gonadotropin level.
ISSN:0919-8172
1442-2042
DOI:10.1111/j.1442-2042.1998.tb00610.x