Culture-negative endocarditis caused by Bartonella henselae

A 4-year-old girl presented with clinical evidence of infective endocarditis involving her aortic valve, but blood cultures were sterile. Serologic studies and analysis of resected valve by immunohistochemistry and polymerase chain reaction established the diagnosis of Bartonella henselae endocardit...

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Bibliographic Details
Published in:The Journal of pediatrics 1998-06, Vol.132 (6), p.1051-1054
Main Authors: Baorto, Elizabeth, Payne, R.Mark, Slater, Leonard N., Lopez, Fred, Relman, David A., Min, Kyung-Whan, St. Geme, Joseph W.
Format: Article
Language:English
Subjects:
Antibodies, Bacterial - blood
Aortic Valve - chemistry
Aortic Valve - pathology
Bacterial diseases
Bartonella henselae - isolation & purification
Bartonellosis
Biological and medical sciences
Cat-Scratch Disease - complications
Cat-Scratch Disease - diagnosis
Cat-Scratch Disease - therapy
Child, Preschool
Endocarditis, Bacterial - diagnosis
Endocarditis, Bacterial - microbiology
Endocarditis, Bacterial - surgery
Female
Heart Defects, Congenital - complications
Heart Defects, Congenital - surgery
Human bacterial diseases
Humans
Immunoenzyme Techniques
Immunohistochemistry
Infectious diseases
Medical sciences
Polymerase Chain Reaction
Tropical bacterial diseases
Tropical medicine
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Summary:A 4-year-old girl presented with clinical evidence of infective endocarditis involving her aortic valve, but blood cultures were sterile. Serologic studies and analysis of resected valve by immunohistochemistry and polymerase chain reaction established the diagnosis of Bartonella henselae endocarditis. Clinicians should be aware that B. henselae can cause apparent culture-negative endocarditis in children. (J Pediatr 1998;132:1051-4.)
ISSN:0022-3476
1097-6833
DOI:10.1016/S0022-3476(98)70410-X