Detrusor hypocontractility in children with posterior urethral valves arises before puberty

Objectives To assess prepubertal boys with posterior urethral valves (PUV) using an analysis of pressure‐flow studies to evaluate the voiding phase and thus determine if myogenic failure (hypocontractility) arises before puberty and if it can be detected early. Patients and methods Eleven boys (8–13...

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Bibliographic Details
Published in:British Journal of Urology 1998-05, Vol.81 (s3), p.81-85
Main Authors: De Gennaro, M., Capitanucci, M.L., Capozza, N., Caione, P., Mosiello, G., Silveri, M.
Format: Article
Language:English
Subjects:
Adolescent
bladder dysfunction
boys
Child
Child, Preschool
Humans
Muscle Contraction
Posterior urethral valves
Pressure
pressure‐flow analysis
Urethra - abnormalities
Urinary Bladder Diseases - physiopathology
Urination - physiology
Urodynamics
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Summary:Objectives To assess prepubertal boys with posterior urethral valves (PUV) using an analysis of pressure‐flow studies to evaluate the voiding phase and thus determine if myogenic failure (hypocontractility) arises before puberty and if it can be detected early. Patients and methods Eleven boys (8–13 years old) with PUV underwent urodynamics and the results were analysed using pressure‐flow mathematical analysis (PFA) of the following variables of detrusor activity: contraction velocity (Vdet ), detrusor contractile power expressed as power factor (WF) and Schafer’s diagram, which differentiates a ‘strong’, ‘normal’ and ‘weak’ detrusor. Vdet and WF were compared with normal values previously determined in boys of similar age and considered ‘low’ if more than 2 SDs below the mean. The results of PFA were compared with standard pressure‐flow studies and the three classical urodynamic patterns in boys with PUV, as determined by voiding symptoms. The subsequent PFA of seven of the 11 boys were also assessed as they had undergone previous urodynamics when
ISSN:0007-1331
1464-410X
DOI:10.1046/j.1464-410x.1998.00014.x