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Monte Carlo-Assisted Voxel Source Kernel Method (MAVSK) for Internal Beta Dosimetry
A method is described for the determination of patient-specific organ beta doses given a known cumulated internal radioactivity distribution. A voxel source kernel for 90Y analogous to the point source function was simulated. Dose to each organ of interest could then be estimated by convolving the v...
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Published in: | Nuclear medicine and biology 1998-05, Vol.25 (4), p.423-433 |
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Main Authors: | , , , |
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container_end_page | 433 |
container_issue | 4 |
container_start_page | 423 |
container_title | Nuclear medicine and biology |
container_volume | 25 |
creator | Liu, An Williams, Lawrence E. Wong, Jeffrey Y.C. Raubitschek, Andrew A. |
description | A method is described for the determination of patient-specific organ beta doses given a known cumulated internal radioactivity distribution. A voxel source kernel for
90Y analogous to the point source function was simulated. Dose to each organ of interest could then be estimated by convolving the voxel source kernel with the patient’s 3-D volume with known radioactivity assigned to each voxel. The dose calculation on eight organs took less than 1 min per patient using a Sun Sparc10 workstation. |
doi_str_mv | 10.1016/S0969-8051(98)00002-X |
format | article |
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subjects | Absorbed beta dose Applied radiobiology (equipment, dosimetry...) Biological and medical sciences Biological effects of radiation Fundamental and applied biological sciences. Psychology Humans Monte Carlo Method Neoplasms - radiotherapy Radioimmunotherapy Radioimmunotherapy - methods Radiotherapy Planning, Computer-Assisted Tissues, organs and organisms biophysics Y-90 Yttrium Radioisotopes |
title | Monte Carlo-Assisted Voxel Source Kernel Method (MAVSK) for Internal Beta Dosimetry |
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