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Membrane fusion: All done with SNAREpins?

SNARE proteins are sufficient to fuse artificial membranes together. In the cell, vesicle transport may rely on fusion mediated by interaction between vesicle (v) and target (t) SNAREs, whereas the homotypic fusion of organelle biogenesis may be mediated by t-SNARE–t-SNARE interaction.

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Bibliographic Details
Published in:Current biology 1998-05, Vol.8 (11), p.R390-R393
Main Author: Edwardson, J.Michael
Format: Article
Language:English
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Summary:SNARE proteins are sufficient to fuse artificial membranes together. In the cell, vesicle transport may rely on fusion mediated by interaction between vesicle (v) and target (t) SNAREs, whereas the homotypic fusion of organelle biogenesis may be mediated by t-SNARE–t-SNARE interaction.
ISSN:0960-9822
1879-0445
DOI:10.1016/S0960-9822(98)70245-3