Pre-operative echocardiographic abnormalities and adverse outcome following renal transplantation

Premature cardiovascular disease is now the leading cause of death in renal transplant recipients. Although patients with progressive renal disease have many of the conventional risk factors for cardiovascular disease these do not have the same predictive power as they do in the general population....

Full description

Saved in:
Bibliographic Details
Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 1998-06, Vol.13 (6), p.1499-1505
Main Authors: MCGREGOR, E, JARDINE, A. G, MURRAY, L. S, DARGIE, H. J, RODGER, R. S. C, JUNOR, B. J. R, MCMILLAN, M. A, BRIGGS, J. D
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Biological and medical sciences
Cardiovascular Diseases - diagnostic imaging
Cardiovascular Diseases - etiology
Cardiovascular Diseases - physiopathology
Cohort Studies
Echocardiography
Female
Humans
Hypertrophy, Left Ventricular - diagnostic imaging
Hypertrophy, Left Ventricular - etiology
Hypertrophy, Left Ventricular - physiopathology
Kidney Failure, Chronic - complications
Kidney Failure, Chronic - diagnostic imaging
Kidney Failure, Chronic - surgery
Kidney Transplantation - adverse effects
Kidney Transplantation - physiology
Male
Medical sciences
Middle Aged
Multivariate Analysis
Risk Factors
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the urinary system
Survival Analysis
Ventricular Function, Left
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Premature cardiovascular disease is now the leading cause of death in renal transplant recipients. Although patients with progressive renal disease have many of the conventional risk factors for cardiovascular disease these do not have the same predictive power as they do in the general population. Echocardiographic abnormalities, notably left ventricular hypertrophy, have been shown to be associated with adverse outcome in patients on dialysis. The echocardiograms were studied from 141 patients who were examined on the eve of renal transplantation between 1988 and 1990 to try to identify factors predicting outcome. Thirty-four patients have since died, 22 of cardiovascular disease. Ninety-three of the survivors and 27 of the dead patients had echocardiographic traces suitable for analysis. Left ventricular mass index was increased in those patients who died (median 167 vs 134 g/m2; P=0.03), as were end-systolic (4.3 vs 3.4 cm; P
ISSN:0931-0509
1460-2385
1460-2385
DOI:10.1093/ndt/13.6.1499