Competing causes of death for primary breast cancer

A patient's likelihood of dying from breast cancer or another cause can be assessed with competing risks analyses. Data for a cohort of 678 patients with primary invasive breast cancer accrued from 1971 to 1990, updated to 1995, included cause of death (e.g., breast cancer vs. other cause). We...

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Bibliographic Details
Published in:Annals of surgical oncology 1998-06, Vol.5 (4), p.368-375
Main Authors: Fish, E B, Chapman, J A, Link, M A
Format: Article
Language:English
Subjects:
Adult
Age
Aged
Breast cancer
Breast Neoplasms - mortality
Breast Neoplasms - therapy
Cause of Death
Chemotherapy
Combined Modality Therapy
Death
Female
Health risk assessment
Humans
Invasiveness
Life span
Mastectomy
Medical prognosis
Middle Aged
Multivariate Analysis
Patients
Radiation therapy
Regression Analysis
Risk
Survival Analysis
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Summary:A patient's likelihood of dying from breast cancer or another cause can be assessed with competing risks analyses. Data for a cohort of 678 patients with primary invasive breast cancer accrued from 1971 to 1990, updated to 1995, included cause of death (e.g., breast cancer vs. other cause). We investigated the effects of age, tumor size, nodal status, ER, PgR, and adjuvant therapy (hormones, chemotherapy, radiotherapy) on type of death and time to death for patients of all ages and for those over the age of 65 years. Although there were no significant univariate differences in breast cancer death rates by age group (P=0.94), more patients over the age of 65 years died from other causes (41/207 [20%] of those older than 65 years vs. 16/471 [3%] of those younger than 65 years; P
ISSN:1068-9265
1534-4681
DOI:10.1007/BF02303502