Uncoupling protein-3 expression in skeletal muscle and free fatty acids in obesity

Researchers investigated whether mRNA expression of UCP2 and UCP3 in human vastus lateralis muscle was correlated with variables related to fat or glucose metabolism and with resting energy expenditure in a mixed population of obese patients and obese patients with type 2 diabetes.

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Bibliographic Details
Published in:The Lancet (British edition) 1998-06, Vol.351 (9120), p.1933-1933
Main Authors: Boss, Olivier, Bobbioni-Harsch, Elisabetta, Assimacopoulos-Jeannet, Francoise, Muzzin, Patrick, Munger, Robert, Giacobino, Jean-Paul, Golay, Alain
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Carrier Proteins - biosynthesis
Diabetes
Diabetes Mellitus - metabolism
Diabetes Mellitus, Type 2 - metabolism
Energy Metabolism
Fatty Acids, Nonesterified - metabolism
Female
Gene Expression
Humans
Ion Channels
Male
Medical research
Medical sciences
Membrane Transport Proteins
Metabolic diseases
Middle Aged
Mitochondria - metabolism
Mitochondria, Muscle - metabolism
Mitochondrial Proteins
Muscle, Skeletal - metabolism
Muscular system
Obesity
Obesity - metabolism
Protein Biosynthesis
Proteins
Ribonucleic acid
RNA
RNA, Messenger - genetics
Uncoupling Protein 2
Uncoupling Protein 3
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Description
Summary:Researchers investigated whether mRNA expression of UCP2 and UCP3 in human vastus lateralis muscle was correlated with variables related to fat or glucose metabolism and with resting energy expenditure in a mixed population of obese patients and obese patients with type 2 diabetes.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(05)78617-7