Changes in plasma lipoproteins after cardiac rehabilitation in patients not on lipid-lowering drugs

The extent to which a conventional cardiac rehabilitation programme can influence plasma lipoproteins was investigated in a prospective study. The relationship between changes in plasma lipoproteins and baseline characteristics, as well as variables related to the physical training and to dietary ha...

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Bibliographic Details
Published in:European heart journal 1990-08, Vol.11 (8), p.722-729
Main Authors: BAARDMAN, T., FIORETTI, P., TOL, A. VAN, ERDMAN, R. A. M., WOEZIK, H. VAN MEURS-VAN, KAZEMIER, M.
Format: Article
Language:English
Subjects:
Cardiac rehabilitation
Cholesterol - blood
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Female
Heart Diseases - blood
Heart Diseases - diet therapy
Heart Diseases - rehabilitation
Humans
Lipoproteins - blood
Male
Middle Aged
Physical Education and Training
plasma lipoproteins
Prospective Studies
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Summary:The extent to which a conventional cardiac rehabilitation programme can influence plasma lipoproteins was investigated in a prospective study. The relationship between changes in plasma lipoproteins and baseline characteristics, as well as variables related to the physical training and to dietary habits were assessed in 77 cardiac patients. All patients participated in a physical training programme, including general dietary advice. Patients who received lipid-lowering drugs were excluded from this study. Total plasma cholesterol decreased from 7.1 ±1.6 to 6.8 ±1.2 mmol l−1 (P < 0.05), but it remained high in many patients, 61% having a level above 6.5 mmol l−1. The high and low-density lipoprotein fractions (HDL-and LDL-cholesterol), and the ratio of total cholesterol to HDL-cholesterol, did not change significantly. The change in total plasma cholesterol was greatest (P< 0.05) in patients who changed their diet in the recommended direction, and was poorly related to the change in maximal workload. It is concluded that a combination of general dietary advice and moderate physical exercise training is followed by a small reduction in total plasma cholesterol levels without changing HDL-cholesterol, and that cardiac rehabilitation should include strict programmes for the reduction of elevated plasma cholesterol.
ISSN:0195-668X
1522-9645
DOI:10.1093/oxfordjournals.eurheartj.a059787