Solitary extramedullary plasmacytoma in the retroperitoneum

• Published in: American journal of hematology 1998-07, Vol.58 (3), p.235-238
• Main Authors: Chen, Tse‐Ching, Wu, Jin‐Hou, Ng, Kwai‐Fong, Lien, Jau‐Min, Hung, Chien‐Fu
• Format: Article
• Language: English
• Subjects: Adult; Biological and medical sciences; Cholestasis, Extrahepatic - diagnosis; Diagnosis, Differential; extramedullary plasmacytoma; Hematologic and hematopoietic diseases; Humans; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis; Male; Medical sciences; obstructive jaundice; Plasmacytoma - diagnosis; Retroperitoneal Neoplasms - diagnosis; retroperitoneum; thrombosis; Thrombosis - diagnosis; Vena Cava, Inferior
• ISSN: 0361-8609; 1096-8652
• DOI: 10.1002/(SICI)1096-8652(199807)58:3<235::AID-AJH13>3.0.CO;2-8

Solitary extramedullary plasmacytoma is an uncommon neoplasm and occurs most frequently in the upper respiratory tract. Herein, we reported a solitary extramedullary plasmacytoma in the retroperitoneum. A 28‐year‐old man presented with obstructive jaundice and a retroperitoneal tumor. Ultrasound‐guided biopsy confirmed that the lesion was a plasma cell neoplasm. A detailed investigation showed that no other sites were involved. The tumor got a moderate reduction following local irradiation, and a complete remission was achieved after 12 courses of adjuvant chemotherapy. Therefore, the possibility of a solitary extramedullary plasmacytoma should be considered in the differential diagnosis of obstructive jaundice without a history of multiple myeloma. Am. J. Hematol. 58:235–238, 1998. © 1998 Wiley‐Liss, Inc.