Natural killer cell lymphoma in cytology: Breaking all the rules-a case report

A testicular mass aspirate was received from a 22‐yr‐old patient with known non‐Hodgkin's lymphoma. The cells were large and pleomorphic, occurring in syncytial fragments and demonstrating abundant cytoplasm. No lymphoglandular bodies were seen. As characteristic lymphoma criteria were not pres...

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Bibliographic Details
Published in:Diagnostic cytopathology 1998-07, Vol.19 (1), p.9-11
Main Authors: Wright, Colleen A., Cooper, Kum, Leiman, Gladwyn, Davidge-Pitts, Marilyn
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Biopsy, Needle
CD-56
CD56 Antigen - analysis
Cytodiagnosis
Diagnosis, Differential
fine-needle aspirate
Germinoma
Hematologic and hematopoietic diseases
Humans
Immunophenotyping
Killer Cells, Natural - immunology
Killer Cells, Natural - pathology
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
lymphoma
Lymphoma, Large B-Cell, Diffuse - diagnosis
Lymphoma, T-Cell - diagnosis
Male
Medical sciences
natural killer cell lymphoma
Seminiferous Tubules - pathology
T-natural killer cells
Testicular Neoplasms - diagnosis
Testicular Neoplasms - pathology
testicular tumor
Testis - pathology
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Summary:A testicular mass aspirate was received from a 22‐yr‐old patient with known non‐Hodgkin's lymphoma. The cells were large and pleomorphic, occurring in syncytial fragments and demonstrating abundant cytoplasm. No lymphoglandular bodies were seen. As characteristic lymphoma criteria were not present, a cytodiagnosis of germ‐cell tumor was suggested, and testicular biopsy advised. The final histopathology report, however, was of a CD 56‐positive (large‐cell) T‐natural killer cell lymphoma, of which this appears to be the first example described and illustrated cytologically. Diagn. Cytopathol. 1998;19:9–11. © 1998 Wiley‐Liss, Inc.
ISSN:8755-1039
1097-0339
DOI:10.1002/(SICI)1097-0339(199807)19:1<9::AID-DC3>3.0.CO;2-B