Malignant tumours of the submandibular salivary gland: a 15-year review

Malignant tumours of the submandibular salivary gland are rare, difficult to distinguish clinically from benign disease and often only diagnosed after initial excision of the enlarged gland. In this study of 70 patients (46 male, 24 female) with a mean age of 64 years (range 17–94), and an average d...

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Bibliographic Details
Published in:British journal of plastic surgery 1998-04, Vol.51 (3), p.181-185
Main Authors: Camilleri, I.G., Malata, C.M., McLean, N.R., Kelly, C.G.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Biological and medical sciences
Female
Follow-Up Studies
Humans
Male
Medical sciences
Middle Aged
Neoplasm Staging
Otorhinolaryngology. Stomatology
Prognosis
Radiotherapy, Adjuvant
Retrospective Studies
Submandibular Gland Neoplasms - pathology
Submandibular Gland Neoplasms - radiotherapy
Submandibular Gland Neoplasms - surgery
Survival Rate
Tumors
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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Summary:Malignant tumours of the submandibular salivary gland are rare, difficult to distinguish clinically from benign disease and often only diagnosed after initial excision of the enlarged gland. In this study of 70 patients (46 male, 24 female) with a mean age of 64 years (range 17–94), and an average duration of symptoms of 3 months, a painless submandibular swelling was the most common presentation. Of the 69 primary tumours, the most frequent histological types were adenoid cystic carcinomas (26 patients, 37%) and carcinoma ex-PSA (18 patients, 26%). One tumour was metastatic in origin, arising from a parotid primary. A total of 65 patients were treated by primary excision of the gland while five patients who presented with advanced disease were treated by radiotherapy alone. Adjuvant postoperative radiotherapy was utilised in 53 (75%) of patients. After a mean follow-up of 5 years, 32 (46%) of patients are still alive. Metastatic disease accounted for 21 deaths (30%). The clinical stage at presentation was the most significant factor predicting survival.
ISSN:0007-1226
1465-3087
DOI:10.1054/bjps.1996.0210