Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8)

Discovered only 4 years ago (Chang et al., 1994), the eighth human herpesvirus (HHV-8), or Kaposi's sarcoma-associated herpesvirus (KSHV), has rapidly become the focus of intensive research. Although still limited, the presently available data provide compelling evidence that KSHV/HHV-8 is the...

Full description

Saved in:
Bibliographic Details
Published in:Journal of general virology 1998-07, Vol.79 ( Pt 7) (7), p.1573-1591
Main Author: Schulz, T F
Format: Article
Language:English
Subjects:
AIDS/HIV
Gene Expression
Genes, Viral
Genetic Variation
Genome, Viral
Herpesvirus 8, Human - classification
Herpesvirus 8, Human - genetics
Herpesvirus 8, Human - growth & development
Herpesvirus 8, Human - ultrastructure
Humans
Lymphoma - virology
Pleural Effusion, Malignant - virology
Sarcoma, Kaposi - epidemiology
Sarcoma, Kaposi - virology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Discovered only 4 years ago (Chang et al., 1994), the eighth human herpesvirus (HHV-8), or Kaposi's sarcoma-associated herpesvirus (KSHV), has rapidly become the focus of intensive research. Although still limited, the presently available data provide compelling evidence that KSHV/HHV-8 is the long-sought-after infectious cause of Kaposi's sarcoma (KS) and that it is thus a new human tumour virus. In this review, I discuss the molecular and epidemiological evidence on which this conclusion is based.
ISSN:0022-1317
1465-2099
DOI:10.1099/0022-1317-79-7-1573