Human influenza virus A/HongKong/156/97 (H5N1) infection

Introduction of influenza viruses with gene segments of avian origin into the human population may result in the emergence of new pathogenic human influenza viruses. The recent infection of a 3-year-old boy with an influenza A (H5N1) virus of avian origin can be considered as an example of such an e...

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Bibliographic Details
Published in:Vaccine 1998-05, Vol.16 (9), p.977-978
Main Authors: Claas, Eric C.J., de Jong, Jan C., van Beek, Ruud, Rimmelzwaan, Guus F., Osterhaus, Albert D.M.E.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Chickens
Child, Preschool
Disease Outbreaks - veterinary
H5N1 subtype
Hong Kong - epidemiology
Human viral diseases
Humans
Infectious diseases
Influenza A virus - classification
Influenza A virus - genetics
Influenza A virus - pathogenicity
Influenza A Virus, H5N1 Subtype
Influenza in Birds - epidemiology
Influenza in Birds - virology
influenza virus
Influenza, Human - epidemiology
Influenza, Human - transmission
Influenza, Human - virology
Male
Medical sciences
pandemic
Phylogeny
Recombination, Genetic
Viral diseases
Viral diseases of the respiratory system and ent viral diseases
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Summary:Introduction of influenza viruses with gene segments of avian origin into the human population may result in the emergence of new pathogenic human influenza viruses. The recent infection of a 3-year-old boy with an influenza A (H5N1) virus of avian origin can be considered as an example of such an event. However, this virus, influenza A/Hong Kong/156/97 (H5N1) and the 17 additional H5N1 viruses isolated from humans by the end of 1997 lack the ability to spread efficiently amongst humans and therefore have limited pandemic potential. However, the possibility of reassortment of these viruses with currently circulating human viruses illustrates the need for pandemic preparedness.
ISSN:0264-410X
1873-2518
DOI:10.1016/S0264-410X(98)00005-X