Cytology of neoplastic meningosis

Where a leptomeningeal carcinomatosis is clinically diagnosed, evidence should be provided of tumor cells in the CSF. Not necessarily in the first specimen, but in the course of the illness. The staining of the cells with the Pappenheim method generally provides sufficient information about the cell...

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Bibliographic Details
Published in:Journal of neuro-oncology 1998-06, Vol.38 (2-3), p.121-125
Main Author: KÖLMEL, H. W
Format: Article
Language:English
Subjects:
Biological and medical sciences
Brain cancer
Brain Neoplasms - cerebrospinal fluid
Brain Neoplasms - pathology
Brain tumors
Cerebrospinal fluid
Chemotherapy
Cytology
Humans
Leukemic Infiltration - pathology
Medical sciences
Meningeal Neoplasms - cerebrospinal fluid
Meningeal Neoplasms - secondary
Meninges
Meninges - pathology
Metastases
Neurology
Tumor cells
Tumors
Tumors of the nervous system. Phacomatoses
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Description
Summary:Where a leptomeningeal carcinomatosis is clinically diagnosed, evidence should be provided of tumor cells in the CSF. Not necessarily in the first specimen, but in the course of the illness. The staining of the cells with the Pappenheim method generally provides sufficient information about the cells. The identification of cells in metastases of epithelial tumours is not difficult for anyone with some experience. Identifying cells from primary brain tumours - which however only rarely cause meningosis - can sometimes be more difficult. Attention should be paid to whether the cells occur in clusters or singly. However, extreme caution is called for. The cytological monitoring of the CSF is an essential part of chemotherapy or radiation treatment.
ISSN:0167-594X
1573-7373
DOI:10.1023/A:1005970406557