Birth-cohort changes in the rates of mania

Secular changes in the rates of mania have been reported in the relatives of affectively ill patients, and the present study is an independent replication of these findings in a large probability sample of a community. Data from the five U.S. sites of the National Institute of Mental Health's E...

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Bibliographic Details
Published in:Psychiatry research 1990-07, Vol.33 (1), p.31-37
Main Authors: Lasch, Kathryn, Weissman, Myrna, Wickramaratne, Priya, Livingston Bruce, Martha
Format: Article
Language:English
Subjects:
Adult
affective disorders
Aged
Aged, 80 and over
Bipolar Disorder - epidemiology
Cohort Studies
Cross-Sectional Studies
Depressive Disorder - epidemiology
Epidemiology
Female
Humans
Incidence
Life Tables
life-table analysis
Male
Middle Aged
Risk Factors
United States - epidemiology
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Summary:Secular changes in the rates of mania have been reported in the relatives of affectively ill patients, and the present study is an independent replication of these findings in a large probability sample of a community. Data from the five U.S. sites of the National Institute of Mental Health's Epidemiologic Catchment Area study (ECA), a community survey of adults, are presented. A total of 17,827 respondents were divided into eight birth cohorts, each spanning a 10-year interval. Actuarial life-table analyses showed a greater cumulative risk of mania for white men and women from the three most recently born cohorts (i.e., those born after 1935). The Wilcoxon test for homogeneity indicated an overall significant difference by birth cohort. These findings in a community sample are consistent with those previously reported in relatives of affectively ill patients. The results support the hypothesis that birth cohort changes have occurred in the risk of mania and that the risk was greatest in the post-1935 cohorts.
ISSN:0165-1781
1872-7123
DOI:10.1016/0165-1781(90)90146-V