Human Herpesvirus 8 as a Potential Sexually Transmitted Agent in Honduras

The seroprevalence of human herpesvirus 8 (HHV-8) was studied in 326 human immunodeficiency virus (HIV)-positive and -negative persons from Honduras; women constituted 77% (n = 251) of the subjects. Sera were tested for lytic HHV-8 antibodies by an IFA, and positive samples were confirmed by a radio...

Full description

Saved in:
Bibliographic Details
Published in:The Journal of infectious diseases 1998-08, Vol.178 (2), p.547-551
Main Authors: Sosa, C., Klaskala, W., Chandran, B., Soto, R., Sieczkowski, L., Wu, M. H., Baum, M., Wood, C.
Format: Article
Language:English
Subjects:
AIDS
AIDS-Related Opportunistic Infections - epidemiology
AIDS-Related Opportunistic Infections - immunology
AIDS-Related Opportunistic Infections - transmission
AIDS-Related Opportunistic Infections - virology
AIDS/HIV
Antibodies
Antibodies, Viral - blood
Biological and medical sciences
Cell lines
Concise Communications
Female
Herpesviridae Infections - epidemiology
Herpesviridae Infections - immunology
Herpesviridae Infections - transmission
Herpesviridae Infections - virology
Herpesvirus 8, Human - immunology
HIV
Honduras - epidemiology
Human herpesvirus 8
Human viral diseases
Humans
Infections
Infectious diseases
Kaposi sarcoma
Male
Medical sciences
Men
Predisposing factors
Prevalence
Risk Factors
Seroepidemiologic studies
Sexually Transmitted Diseases, Viral - epidemiology
Sexually Transmitted Diseases, Viral - transmission
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The seroprevalence of human herpesvirus 8 (HHV-8) was studied in 326 human immunodeficiency virus (HIV)-positive and -negative persons from Honduras; women constituted 77% (n = 251) of the subjects. Sera were tested for lytic HHV-8 antibodies by an IFA, and positive samples were confirmed by a radioimmunoprecipitation assay. Of the 326 persons tested, 58 (17.8%) had HHV-8 antibodies. Among the HIV-infected women, 22.7% were seropositive; 11.3% of the HIV-negative women were seropositive. HHV-8 seroprevalence was almost four times higher in HIV-positive female commercial sex workers (36%) than in HIV-negative female non-commercial sex workers (9.9%; odds ratio = 3.8, 95% confidence interval = 1.1–13; P = 0.01), suggesting that commercial sex work is a risk factor for HHV-8 infection. In the men studied, the overall HHV-8 seroprevalence was 22.6%, with a seropositivity rate of 28% for HIV-positive men compared with 12% for HIV-negative men.
ISSN:0022-1899
1537-6613
DOI:10.1086/517471