Variation in taste of topical lignocaine anaesthesia for gastroscopy

Aim: To study the distribution and determinants of taste variation for lignocaine spray (Xylocaine; Astra Pharmaceuticals, King’s Langley, UK). Methods: Sixty‐nine patients (male:female 49:20, mean age 48.5 years) attending for open access upper gastrointestinal endoscopy were studied. Taste perceiv...

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Bibliographic Details
Published in:Alimentary pharmacology & therapeutics 1998-07, Vol.12 (7), p.685-686
Main Authors: ASANTE, M. A, NORTHFIELD, T. C
Format: Article
Language:English
Subjects:
Administration, Topical
Adult
Aerosols
Aged
Aged, 80 and over
Anesthetics, Local
Anesthetics. Neuromuscular blocking agents
Biological and medical sciences
Female
Gastroscopy
Humans
Lidocaine
Male
Medical sciences
Middle Aged
Neuropharmacology
Pharmacology. Drug treatments
Taste
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Summary:Aim: To study the distribution and determinants of taste variation for lignocaine spray (Xylocaine; Astra Pharmaceuticals, King’s Langley, UK). Methods: Sixty‐nine patients (male:female 49:20, mean age 48.5 years) attending for open access upper gastrointestinal endoscopy were studied. Taste perceived after applying 4 doses (40 mg) of lignocaine spray to the oro‐pharynx was recorded prior to endoscopy. Results: 37/69 (54%, 95% CI: 41–66%) perceived the taste of the lignocaine spray as bitter, whilst 24/69 (35%, 95% CI: 24–47%) and 6/69 (9%, 95% CI: 3–18%) perceived the taste as either fruity/sweet or tasteless. The variation in taste did not correlate with either demographic features or H. pylori infection, but duodenal ulceration was slightly more common amongst bitter tasters. Conclusion: The taste of lignocaine is not uniform, but the basis of this variability is uncertain.
ISSN:0269-2813
1365-2036
DOI:10.1046/j.1365-2036.1998.00355.x