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Molecular regulation of the life cycle of African trypanosomes
Preventing the transmission of African trypanosomes between mammalian hosts has been one of the most effective mechanisms to date for the control of these important parasites. Hence, understanding the mechanisms through which they control their life cycle in molecular terms could provide valuable st...
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| Published in: | Trends in parasitology 2004, Vol.20 (1), p.40-47 |
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| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c407t-1164818547cfd6b9e8db3392fc1f62922e0463f52aa7321694b1bedd38273f4e3 |
| container_end_page | 47 |
| container_issue | 1 |
| container_start_page | 40 |
| container_title | Trends in parasitology |
| container_volume | 20 |
| creator | Matthews, Keith R. Ellis, James R. Paterou, Athina |
| description | Preventing the transmission of African trypanosomes between mammalian hosts has been one of the most effective mechanisms to date for the control of these important parasites. Hence, understanding the mechanisms through which they control their life cycle in molecular terms could provide valuable strategies for restricting the impact of sleeping sickness. Over the past two to three years, the study of the molecular cell biology of trypanosome life cycle progression has made considerable advances. Here, these advances are placed in the context of the biology of the parasite, to provide an integrated overview of developmental events in
Trypanosoma brucei. |
| doi_str_mv | 10.1016/j.pt.2003.10.016 |
| format | article |
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| identifier | ISSN: 1471-4922 |
| ispartof | Trends in parasitology, 2004, Vol.20 (1), p.40-47 |
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| language | eng |
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| source | Elsevier |
| subjects | Animals Biological and medical sciences Disease Transmission, Infectious DNA, Protozoan - genetics DNA, Protozoan - metabolism Fundamental and applied biological sciences. Psychology Gene Expression Regulation Gene Expression Regulation, Developmental Humans Life Cycle Stages - genetics Life cycle. Host-agent relationship. Pathogenesis Protozoa RNA, Messenger - genetics RNA, Messenger - metabolism Trypanosoma - genetics Trypanosoma - growth & development Trypanosoma brucei Trypanosomiasis, African - blood Trypanosomiasis, African - parasitology Trypanosomiasis, African - transmission |
| title | Molecular regulation of the life cycle of African trypanosomes |
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