Increased neutrophil aggregability in coronary artery disease

The purpose of this investigation was to study neutrophil (PMN) aggregation in the aorta and coronary sinus of 20 patients with angiographically documented coronary artery disease (group I) compared with eight patients with normal coronary arteries (group II). PMNs were separated from the other bloo...

Full description

Saved in:
Bibliographic Details
Published in:European heart journal 1990-09, Vol.11 (9), p.814-818
Main Authors: RICEVUTI, G., DE SERVI, S., MAZZONE, A., ANGOLI, L., GHIO, S., SPECCHIA, G.
Format: Article
Language:English
Subjects:
aggregation
Aorta - pathology
Cell Aggregation
coronary artery disease
Coronary Disease - blood
Coronary Disease - pathology
Coronary Vessels - pathology
Female
Humans
Male
Middle Aged
Neutrophil
Neutrophils - physiology
Smoking - blood
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The purpose of this investigation was to study neutrophil (PMN) aggregation in the aorta and coronary sinus of 20 patients with angiographically documented coronary artery disease (group I) compared with eight patients with normal coronary arteries (group II). PMNs were separated from the other blood components and their aggregation response to Ca2+ ionophore A 23187 1 × 10−5 M (final concentration) was measured. Group I patients had higher aggregating activity in the coronary sinus than in the aorta (24.9± 3.7 vs 18.7± 3.4 average maximum ΔT, P
ISSN:0195-668X
1522-9645
DOI:10.1093/oxfordjournals.eurheartj.a059801