Increased neutrophil aggregability in coronary artery disease

The purpose of this investigation was to study neutrophil (PMN) aggregation in the aorta and coronary sinus of 20 patients with angiographically documented coronary artery disease (group I) compared with eight patients with normal coronary arteries (group II). PMNs were separated from the other bloo...

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Published in:European heart journal 1990-09, Vol.11 (9), p.814-818
Main Authors: RICEVUTI, G., DE SERVI, S., MAZZONE, A., ANGOLI, L., GHIO, S., SPECCHIA, G.
Format: Article
Language:English
Subjects:
aggregation
Aorta - pathology
Cell Aggregation
coronary artery disease
Coronary Disease - blood
Coronary Disease - pathology
Coronary Vessels - pathology
Female
Humans
Male
Middle Aged
Neutrophil
Neutrophils - physiology
Smoking - blood
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container_end_page 818
container_issue 9
container_start_page 814
container_title European heart journal
container_volume 11
creator RICEVUTI, G.
DE SERVI, S.
MAZZONE, A.
ANGOLI, L.
GHIO, S.
SPECCHIA, G.
description The purpose of this investigation was to study neutrophil (PMN) aggregation in the aorta and coronary sinus of 20 patients with angiographically documented coronary artery disease (group I) compared with eight patients with normal coronary arteries (group II). PMNs were separated from the other blood components and their aggregation response to Ca2+ ionophore A 23187 1 × 10−5 M (final concentration) was measured. Group I patients had higher aggregating activity in the coronary sinus than in the aorta (24.9± 3.7 vs 18.7± 3.4 average maximum ΔT, P
doi_str_mv 10.1093/oxfordjournals.eurheartj.a059801
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source Oxford University Press:Jisc Collections:Oxford Journal Archive: Access period 2024-2025
subjects aggregation
Aorta - pathology
Cell Aggregation
coronary artery disease
Coronary Disease - blood
Coronary Disease - pathology
Coronary Vessels - pathology
Female
Humans
Male
Middle Aged
Neutrophil
Neutrophils - physiology
Smoking - blood
title Increased neutrophil aggregability in coronary artery disease
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