Pregnancy, sleep disordered breathing and treatment with nasal continuous positive airway pressure

Objective: To investigate the tolerance, compliance and problems associated with usage of nasal continuous positive airway pressure (CPAP) by pregnant women with sleep disordered breathing (SDB). Patients and method: Twelve pregnant women diagnosed with SDB received polysomnography (PSG) at entry, C...

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Bibliographic Details
Published in:Sleep medicine 2004-01, Vol.5 (1), p.43-51
Main Authors: Guilleminault, Christian, Kreutzer, Martina, Chang, Judy L
Format: Article
Language:English
Subjects:
Adult
Compliance
Disorders of Excessive Somnolence - epidemiology
Electroencephalography
Fatigue
Fatigue - epidemiology
Female
Follow-Up Studies
Humans
Nasal continuous positive airway pressure
Patient Compliance
Polysomnography
Positive-Pressure Respiration - methods
Pregnancy
Severity of Illness Index
Sleep apnea
Sleep Apnea, Obstructive - diagnosis
Sleep Apnea, Obstructive - therapy
Sleep Stages - physiology
Sleepiness
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Summary:Objective: To investigate the tolerance, compliance and problems associated with usage of nasal continuous positive airway pressure (CPAP) by pregnant women with sleep disordered breathing (SDB). Patients and method: Twelve pregnant women diagnosed with SDB received polysomnography (PSG) at entry, CPAP titration, repeat PSG at 6 months gestation (GA) and home monitoring of cardio-respiratory variables at 8 months GA. Compliance was verified by the pressure at the mask. Results from the Epworth sleepiness scale, fatigue scale and visual analogue scales (VAS) for sleepiness, fatigue, and snoring were compared over time. Results: All of the subjects had full term pregnancies and healthy infants. Nightly compliance was at least 4 h initially and 6.5 h at 6 months GA. Nasal CPAP significantly improved all scales compared to entry. VAS scores remained lower at 6 months GA compared to entry. Re-adjustment of CPAP pressure was needed in six subjects at 6 months GA. Conclusion: Nasal CPAP is a safe and effective treatment of SDB during pregnancy.
ISSN:1389-9457
1878-5506
DOI:10.1016/j.sleep.2003.07.001