Viral-associated trichodysplasia in patients who are immunocompromised

Viral-associated trichodysplasia of immunosuppression is a newly described clinicopathologic entity found in patients who are undergoing drug-induced immunosuppression to prevent organ transplant rejection. Patients have numerous erythematous papules concentrated in the central portion of the face a...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2004-02, Vol.50 (2), p.318-322
Main Authors: Sperling, COL Leonard C, Tomaszewski, Maria-Magdalena, Thomas, Douglas A
Format: Article
Language:English
Subjects:
Adolescent
Alopecia - etiology
Alopecia - virology
Biological and medical sciences
Dermatology
Erythema - etiology
Erythema - pathology
Erythema - virology
Facial Dermatoses - etiology
Facial Dermatoses - pathology
Facial Dermatoses - virology
Female
Hair Follicle - pathology
Humans
Immunocompromised Host
Immunosuppression
Immunosuppressive Agents - adverse effects
Immunosuppressive Agents - therapeutic use
Keratins
Kidney Transplantation
Medical sciences
Microscopy, Electron
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Viral-associated trichodysplasia of immunosuppression is a newly described clinicopathologic entity found in patients who are undergoing drug-induced immunosuppression to prevent organ transplant rejection. Patients have numerous erythematous papules concentrated in the central portion of the face and variable degrees of hair loss, most severely affecting facial hair. Histologic findings of facial papules are highly distinctive and unique, and suggest that the entire machinery of the follicular bulb is devoted to the manufacture of inner root sheath-type keratin. Electron microscopy reveals intranuclear viral particles, but precise viral identification has not yet been achieved.
ISSN:0190-9622
1097-6787
DOI:10.1016/S0190-9622(03)01490-7