Lateralization of Epileptic Foci by Neuropsychological Testing in Mesial Temporal Lobe Epilepsy

This study investigated the lateralizing value of neuropsychological testing in presurgical evaluation of mesial temporal lobe epilepsy (MTLE). This study differed from previous ones in that the cutoff values were determined to yield high positive predictive values (PPVs), multiple neuropsychologica...

Full description

Saved in:
Bibliographic Details
Published in:Neuropsychology 2004-01, Vol.18 (1), p.141-151
Main Authors: Kim, Hongkeun, Yi, Sangdoe, Son, Eun Ik, Kim, Jieun
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Biological and medical sciences
Chi-Square Distribution
Demography
Electroencephalography
Epilepsy, Temporal Lobe - classification
Epilepsy, Temporal Lobe - complications
Epilepsy, Temporal Lobe - physiopathology
Epilepsy, Temporal Lobe - surgery
Epileptic Seizures
Evaluation
Female
Functional Laterality - physiology
Human
Humans
Intellectual Disability - etiology
Intellectual Disability - physiopathology
Intelligence
Intelligence Tests
Language Disorders - etiology
Language Disorders - physiopathology
Lateral Dominance
Magnetic Resonance Imaging - methods
Male
Medical sciences
Memory
Neuropsychological Assessment
Neuropsychological Tests
Organic mental disorders. Neuropsychology
Prediction
Predictive Value of Tests
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychosurgery
Sensitivity and Specificity
Temporal Lobe
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study investigated the lateralizing value of neuropsychological testing in presurgical evaluation of mesial temporal lobe epilepsy (MTLE). This study differed from previous ones in that the cutoff values were determined to yield high positive predictive values (PPVs), multiple neuropsychological predictors were considered in combination, and patients with atypical language dominance or low intelligence were not excluded from the sample. The participants were 92 patients with MTLE (left, n = 47; right, n = 45) who showed good postoperative seizure control. With a stringent cutoff criterion, the multiple neuropsychological predictors considered in combination yielded a sensitivity of 15% and a PPV of 93%, and with a less stringent cutoff criterion, a sensitivity of 37% and a PPV of 83%.
ISSN:0894-4105
1931-1559
DOI:10.1037/0894-4105.18.1.141