Relation between calcium absorption and serum calcitriol in normal men: evidence for age-related intestinal resistance to calcitriol

• Published in: European journal of clinical nutrition 2004-02, Vol.58 (2), p.264-269
• Main Authors: Scopacasa, F, Wishart, J M, Horowitz, M, Morris, H A, Need, A G
• Format: Article
• Language: English
• Subjects: 25-Hydroxyvitamin D; Absorptiometry, Photon; Absorption; Adult; Age; Age Factors; Aged; Aged, 80 and over; Australia; Biological and medical sciences; Blood; Bone Density; Bone loss; Bone turnover; Bones; Calcitriol; Calcitriol - blood; Calcium; Calcium (urinary); Calcium - blood; Calcium - pharmacokinetics; Calcium - urine; Calcium absorption; Calcium phosphates; Clinical Nutrition; Comparative analysis; Creatinine; Creatinine - urine; Cross-Sectional Studies; Epidemiology; Excretion; Forearm; Forearm - diagnostic imaging; Humans; Internal Medicine; Intestinal Absorption; Intestine; Male; Males; Medical sciences; Medicine; Medicine & Public Health; Men; Metabolic Diseases; Metals (hemochromatosis...); Middle Aged; original-communication; Other metabolic disorders; Phosphates - urine; Public Health; Radionuclide Imaging; Studies; White people
• ISSN: 0954-3007; 1476-5640
• DOI: 10.1038/sj.ejcn.1601777

Objective : To obtain information on the causes of age-related bone loss in men and the concomitant decline in calcium absorption. Design : Cross-sectional study. Setting : Adelaide, South Australia, Australia. Subjects : A total of 95 healthy, Caucasian men (age range 27–87 y). Results : Calcium absorption declined with age ( r =−0.46, P −0.21, P