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Serial CT Volume and Thrombus Length Measurements after Endovascular Repair of Stanford Type B Aortic Dissection

Purpose: To evaluate the outcome of stent-graft placement in Stanford type B aortic dissection using contrast-enhanced spiral computed tomographic (CT) measurements of true and false lumen volumes and thrombus length. Methods: Among 18 consecutive patients (13 men; mean age 60 years, range 44–79) wh...

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Published in:Journal of endovascular therapy 2004-02, Vol.11 (1), p.1-12
Main Authors: Czermak, Benedikt V., Mallouhi, Ammar, Perkmann, Reinhold, Steingruber, Iris E., Waldenberger, Peter, Neuhauser, Beate, Fraedrich, Gustav, Jung, Tarzis, Jaschke, Werner R.
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cited_by cdi_FETCH-LOGICAL-c2521-340e0f978ad3119488887e81e7c479e43652ea47ee3c9cab117410472fee7b873
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container_title Journal of endovascular therapy
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creator Czermak, Benedikt V.
Mallouhi, Ammar
Perkmann, Reinhold
Steingruber, Iris E.
Waldenberger, Peter
Neuhauser, Beate
Fraedrich, Gustav
Jung, Tarzis
Jaschke, Werner R.
description Purpose: To evaluate the outcome of stent-graft placement in Stanford type B aortic dissection using contrast-enhanced spiral computed tomographic (CT) measurements of true and false lumen volumes and thrombus length. Methods: Among 18 consecutive patients (13 men; mean age 60 years, range 44–79) who underwent endovascular repair of Stanford type B dissection, 12 completed at least a 12-month follow-up, which included CT measurements of true and false lumen volumes and thrombus lengths prior to discharge and at 6 and 12 months postimplantation. Volumes were assessed in 3 different aortic segments (A1, A2, A3) extending from the proximal attachment site of the prosthesis to the aortic bifurcation. In addition, thrombus length was measured to evaluate the influence of clot formation on outcome of the false lumen volume. Results: Mean follow-up was 27 months (range 12–60). Within 12 months, mean true lumen volumes showed statistically significant increases in the A1 (p
doi_str_mv 10.1177/152660280401100101
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Methods: Among 18 consecutive patients (13 men; mean age 60 years, range 44–79) who underwent endovascular repair of Stanford type B dissection, 12 completed at least a 12-month follow-up, which included CT measurements of true and false lumen volumes and thrombus lengths prior to discharge and at 6 and 12 months postimplantation. Volumes were assessed in 3 different aortic segments (A1, A2, A3) extending from the proximal attachment site of the prosthesis to the aortic bifurcation. In addition, thrombus length was measured to evaluate the influence of clot formation on outcome of the false lumen volume. Results: Mean follow-up was 27 months (range 12–60). Within 12 months, mean true lumen volumes showed statistically significant increases in the A1 (p&lt;0.001) and A2 (p=0.003) segments; false lumen volumes showed a significant decrease in the A1 segment (p=0.002) but an insignificant increase in the A2 segment. No substantial volume changes were observed in the A3 segment. Extension of clot formation in the false lumen varied among patients and over time. Length of stent-grafts, percentage of stented dissection length, or visceral arteries originating from the false lumen did not significantly influence thrombus development, nor did these parameters or thrombus formation distal to the prosthesis have a relationship to false lumen volumes. Conclusions: Volumetric analysis after endovascular repair of Stanford type B dissection shows optimal technical outcome in the stented segment, whereas the false lumen in the segment immediately adjacent to the stent-graft seems to be a vulnerable area. Extension of clot formation beyond the endograft seems to be no reliable predictor of outcome.</description><identifier>ISSN: 1526-6028</identifier><identifier>EISSN: 1545-1550</identifier><identifier>DOI: 10.1177/152660280401100101</identifier><identifier>PMID: 14748634</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Adult ; Aged ; Aneurysm, Dissecting - surgery ; Aortic Aneurysm - diagnostic imaging ; Blood Vessel Prosthesis Implantation - adverse effects ; Female ; Humans ; Image Processing, Computer-Assisted ; Logistic Models ; Male ; Middle Aged ; Prospective Studies ; Radiographic Image Enhancement ; Stents ; Thrombosis - etiology ; Tomography, Spiral Computed</subject><ispartof>Journal of endovascular therapy, 2004-02, Vol.11 (1), p.1-12</ispartof><rights>2004 SAGE Publications</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2521-340e0f978ad3119488887e81e7c479e43652ea47ee3c9cab117410472fee7b873</citedby><cites>FETCH-LOGICAL-c2521-340e0f978ad3119488887e81e7c479e43652ea47ee3c9cab117410472fee7b873</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925,79364</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14748634$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Czermak, Benedikt V.</creatorcontrib><creatorcontrib>Mallouhi, Ammar</creatorcontrib><creatorcontrib>Perkmann, Reinhold</creatorcontrib><creatorcontrib>Steingruber, Iris E.</creatorcontrib><creatorcontrib>Waldenberger, Peter</creatorcontrib><creatorcontrib>Neuhauser, Beate</creatorcontrib><creatorcontrib>Fraedrich, Gustav</creatorcontrib><creatorcontrib>Jung, Tarzis</creatorcontrib><creatorcontrib>Jaschke, Werner R.</creatorcontrib><title>Serial CT Volume and Thrombus Length Measurements after Endovascular Repair of Stanford Type B Aortic Dissection</title><title>Journal of endovascular therapy</title><addtitle>J Endovasc Ther</addtitle><description>Purpose: To evaluate the outcome of stent-graft placement in Stanford type B aortic dissection using contrast-enhanced spiral computed tomographic (CT) measurements of true and false lumen volumes and thrombus length. Methods: Among 18 consecutive patients (13 men; mean age 60 years, range 44–79) who underwent endovascular repair of Stanford type B dissection, 12 completed at least a 12-month follow-up, which included CT measurements of true and false lumen volumes and thrombus lengths prior to discharge and at 6 and 12 months postimplantation. Volumes were assessed in 3 different aortic segments (A1, A2, A3) extending from the proximal attachment site of the prosthesis to the aortic bifurcation. In addition, thrombus length was measured to evaluate the influence of clot formation on outcome of the false lumen volume. Results: Mean follow-up was 27 months (range 12–60). Within 12 months, mean true lumen volumes showed statistically significant increases in the A1 (p&lt;0.001) and A2 (p=0.003) segments; false lumen volumes showed a significant decrease in the A1 segment (p=0.002) but an insignificant increase in the A2 segment. No substantial volume changes were observed in the A3 segment. Extension of clot formation in the false lumen varied among patients and over time. Length of stent-grafts, percentage of stented dissection length, or visceral arteries originating from the false lumen did not significantly influence thrombus development, nor did these parameters or thrombus formation distal to the prosthesis have a relationship to false lumen volumes. Conclusions: Volumetric analysis after endovascular repair of Stanford type B dissection shows optimal technical outcome in the stented segment, whereas the false lumen in the segment immediately adjacent to the stent-graft seems to be a vulnerable area. Extension of clot formation beyond the endograft seems to be no reliable predictor of outcome.</description><subject>Adult</subject><subject>Aged</subject><subject>Aneurysm, Dissecting - surgery</subject><subject>Aortic Aneurysm - diagnostic imaging</subject><subject>Blood Vessel Prosthesis Implantation - adverse effects</subject><subject>Female</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>Radiographic Image Enhancement</subject><subject>Stents</subject><subject>Thrombosis - etiology</subject><subject>Tomography, Spiral Computed</subject><issn>1526-6028</issn><issn>1545-1550</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><recordid>eNp9kD1PwzAQhi0EoqXwBxiQJ7ZQn-PE6VhK-ZCKkGhhjRzn0qZK4mDHSP33pGolBiRuuRue95XuIeQa2B2AlGOIeBwznjDBABgDBidkCJGIAogidrq_eRzsiQG5cG7LGAcOcE4GIKRI4lAMSbtEW6qKzlb001S-RqqanK421tSZd3SBzbrb0FdUzlussekcVUWHls6b3Hwrp32lLH3HVpWWmoIuO9UUxvYVuxbpPZ0a25WaPpTOoe5K01ySs0JVDq-Oe0Q-Huer2XOweHt6mU0XgeYRhyAUDFkxkYnKQ4CJSPqRmABKLeQERRhHHJWQiKGeaJX1QgQwIXmBKLNEhiNye-htrfny6Lq0Lp3GqlINGu_ShAGXvcUe5AdQW-OcxSJtbVkru0uBpXvP6V_Pfejm2O6zGvPfyFFsD4wPgFNrTLfG26b_9r_KH7eJhJk</recordid><startdate>200402</startdate><enddate>200402</enddate><creator>Czermak, Benedikt V.</creator><creator>Mallouhi, Ammar</creator><creator>Perkmann, Reinhold</creator><creator>Steingruber, Iris E.</creator><creator>Waldenberger, Peter</creator><creator>Neuhauser, Beate</creator><creator>Fraedrich, Gustav</creator><creator>Jung, Tarzis</creator><creator>Jaschke, Werner R.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200402</creationdate><title>Serial CT Volume and Thrombus Length Measurements after Endovascular Repair of Stanford Type B Aortic Dissection</title><author>Czermak, Benedikt V. ; 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Extension of clot formation in the false lumen varied among patients and over time. Length of stent-grafts, percentage of stented dissection length, or visceral arteries originating from the false lumen did not significantly influence thrombus development, nor did these parameters or thrombus formation distal to the prosthesis have a relationship to false lumen volumes. Conclusions: Volumetric analysis after endovascular repair of Stanford type B dissection shows optimal technical outcome in the stented segment, whereas the false lumen in the segment immediately adjacent to the stent-graft seems to be a vulnerable area. Extension of clot formation beyond the endograft seems to be no reliable predictor of outcome.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>14748634</pmid><doi>10.1177/152660280401100101</doi><tpages>12</tpages></addata></record>
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source SAGE Journals
subjects Adult
Aged
Aneurysm, Dissecting - surgery
Aortic Aneurysm - diagnostic imaging
Blood Vessel Prosthesis Implantation - adverse effects
Female
Humans
Image Processing, Computer-Assisted
Logistic Models
Male
Middle Aged
Prospective Studies
Radiographic Image Enhancement
Stents
Thrombosis - etiology
Tomography, Spiral Computed
title Serial CT Volume and Thrombus Length Measurements after Endovascular Repair of Stanford Type B Aortic Dissection
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