Organic anion transport is the primary function of the SLC17/type I phosphate transporter family

Recently, molecular studies have determined that the SLC17/type I phosphate transporters, a family of proteins initially characterized as phosphate carriers, mediate the transport of organic anions. While their role in phosphate transport remains uncertain, it is now clear that the transport of orga...

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Bibliographic Details
Published in:Pflügers Archiv 2004-02, Vol.447 (5), p.629-635
Main Authors: Reimer, Richard J, Edwards, Robert H
Format: Article
Language:English
Subjects:
Animals
Anions - metabolism
Biological Transport - physiology
Humans
Multigene Family - physiology
Organic Anion Transporters - physiology
Phosphates - metabolism
Proteins
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Summary:Recently, molecular studies have determined that the SLC17/type I phosphate transporters, a family of proteins initially characterized as phosphate carriers, mediate the transport of organic anions. While their role in phosphate transport remains uncertain, it is now clear that the transport of organic anions facilitated by this family of proteins is involved in diverse processes ranging from the vesicular storage of the neurotransmitter glutamate to the degradation and metabolism of glycoproteins.
ISSN:0031-6768
1432-2013
DOI:10.1007/s00424-003-1087-y