Scaffolds for articular cartilage repair

Tissue engineering of articular cartilage seeks to restore the damaged joint surface, inducing repair of host tissues by delivering repair cells, genes, or polypeptide stimulatory factors to the site of injury. A plethora of devices and materials are being examined for their potential to deliver the...

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Bibliographic Details
Published in:Annals of biomedical engineering 2004-01, Vol.32 (1), p.26-34
Main Authors: Frenkel, Sally R, Di Cesare, Paul E
Format: Article
Language:English
Subjects:
Animals
Biomimetic Materials
Cartilage Diseases - physiopathology
Cartilage Diseases - therapy
Cartilage, Articular - cytology
Cartilage, Articular - growth & development
Cartilage, Articular - injuries
Cartilage, Articular - physiology
Cell Adhesion - physiology
Cell Division - physiology
Cells, Cultured
Culture Techniques - methods
Extracellular Matrix - physiology
Humans
Membranes, Artificial
Prostheses and Implants
Regeneration - physiology
Tissue Engineering - methods
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Summary:Tissue engineering of articular cartilage seeks to restore the damaged joint surface, inducing repair of host tissues by delivering repair cells, genes, or polypeptide stimulatory factors to the site of injury. A plethora of devices and materials are being examined for their potential to deliver these agents to wound sites, and to act as scaffolds for ingrowth of new tissue. This review will discuss various promising scaffolds for cartilage tissue engineering applications.
ISSN:0090-6964
1573-9686
DOI:10.1023/B:ABME.0000007788.41804.0d