Loading…
Slipping pumps or proton leaks in oxidative phosphorylation: The local anesthetic bupivacaine causes slip in cytochrome c oxidase of mitochondria
Evidence is presented to show that the local anesthetic bupivacaine causes slip in the mitochondrial proton pump cytochrome c oxidase.
Saved in:
| Published in: | FEBS letters 1990-12, Vol.277 (1), p.131-133 |
|---|---|
| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | |
|---|---|
| cites | cdi_FETCH-LOGICAL-c335t-3473db1b3b494d7e972e994ea78a792d2ee0abe93a703666ab2fb34d7c47cb3e3 |
| container_end_page | 133 |
| container_issue | 1 |
| container_start_page | 131 |
| container_title | FEBS letters |
| container_volume | 277 |
| creator | van Dam, Karel Shinohara, Yasuo Unami, Akira Yoshida, Kenji Terada, Hiroshi |
| description | Evidence is presented to show that the local anesthetic bupivacaine causes slip in the mitochondrial proton pump cytochrome
c oxidase. |
| doi_str_mv | 10.1016/0014-5793(90)80826-5 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_80202762</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0014579390808265</els_id><sourcerecordid>80202762</sourcerecordid><originalsourceid>FETCH-LOGICAL-c335t-3473db1b3b494d7e972e994ea78a792d2ee0abe93a703666ab2fb34d7c47cb3e3</originalsourceid><addsrcrecordid>eNp9kc9u1DAQxi0EKtvCG4DkA0LlkOI_iR33gIQqoJUqcaCcLduZsIbEDnayYh-DN8ZhV3vswbLG85vPM98g9IqSK0qoeE8IratGKn6pyLuWtExUzRO0oa3kFa9F-xRtTshzdJ7zT1LilqozdMaoFIKSDfr7bfDT5MMPPC3jlHFMeEpxjgEPYH5l7AOOf3xnZr8DPG1jLifthxLHcI0ftoCH6MyATYA8b2H2Dttl8jvjjA-AnVkyZJzLJ6uU28_RbVMcS-agmwHHHo9-fY-hS968QM96M2R4ebwv0PfPnx5ubqv7r1_ubj7eV47zZi4TSt5ZarmtVd1JUJKBUjUY2RqpWMcAiLGguJGECyGMZb3lhXS1dJYDv0BvD7pl3t9L6V6PPjsYhjJKXLJuCSNMClbA-gC6FHNO0Osp-dGkvaZEr5vQq816tVkrov9vQjel7PVRf7EjdKeio_Ul_-aYN7k42CcTnM8nrOGNZEwW7MMBg-LFzkPS2XkIDjqfwM26i_7xPv4BXr2oSw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>80202762</pqid></control><display><type>article</type><title>Slipping pumps or proton leaks in oxidative phosphorylation: The local anesthetic bupivacaine causes slip in cytochrome c oxidase of mitochondria</title><source>ScienceDirect Journals</source><creator>van Dam, Karel ; Shinohara, Yasuo ; Unami, Akira ; Yoshida, Kenji ; Terada, Hiroshi</creator><creatorcontrib>van Dam, Karel ; Shinohara, Yasuo ; Unami, Akira ; Yoshida, Kenji ; Terada, Hiroshi</creatorcontrib><description>Evidence is presented to show that the local anesthetic bupivacaine causes slip in the mitochondrial proton pump cytochrome
c oxidase.</description><identifier>ISSN: 0014-5793</identifier><identifier>EISSN: 1873-3468</identifier><identifier>DOI: 10.1016/0014-5793(90)80826-5</identifier><identifier>PMID: 2176610</identifier><identifier>CODEN: FEBLAL</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Anilino Naphthalenesulfonates - pharmacology ; Animals ; Biological and medical sciences ; Bupivacaine - pharmacology ; Cell physiology ; Electron Transport Complex IV - metabolism ; Fundamental and applied biological sciences. Psychology ; Hydrogen-Ion Concentration ; Local anesthetic ; Male ; Mitochondria ; Mitochondria, Liver - drug effects ; Mitochondria, Liver - metabolism ; Molecular and cellular biology ; Oxidative phosphorylation ; Oxidative Phosphorylation - drug effects ; Oxygen Consumption - drug effects ; Proton pump ; Proton-Translocating ATPases - metabolism ; Rats ; Rats, Inbred Strains ; Uncoupling</subject><ispartof>FEBS letters, 1990-12, Vol.277 (1), p.131-133</ispartof><rights>1990</rights><rights>1992 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c335t-3473db1b3b494d7e972e994ea78a792d2ee0abe93a703666ab2fb34d7c47cb3e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0014579390808265$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3536,27901,27902,45756</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=5357227$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2176610$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>van Dam, Karel</creatorcontrib><creatorcontrib>Shinohara, Yasuo</creatorcontrib><creatorcontrib>Unami, Akira</creatorcontrib><creatorcontrib>Yoshida, Kenji</creatorcontrib><creatorcontrib>Terada, Hiroshi</creatorcontrib><title>Slipping pumps or proton leaks in oxidative phosphorylation: The local anesthetic bupivacaine causes slip in cytochrome c oxidase of mitochondria</title><title>FEBS letters</title><addtitle>FEBS Lett</addtitle><description>Evidence is presented to show that the local anesthetic bupivacaine causes slip in the mitochondrial proton pump cytochrome
c oxidase.</description><subject>Anilino Naphthalenesulfonates - pharmacology</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Bupivacaine - pharmacology</subject><subject>Cell physiology</subject><subject>Electron Transport Complex IV - metabolism</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hydrogen-Ion Concentration</subject><subject>Local anesthetic</subject><subject>Male</subject><subject>Mitochondria</subject><subject>Mitochondria, Liver - drug effects</subject><subject>Mitochondria, Liver - metabolism</subject><subject>Molecular and cellular biology</subject><subject>Oxidative phosphorylation</subject><subject>Oxidative Phosphorylation - drug effects</subject><subject>Oxygen Consumption - drug effects</subject><subject>Proton pump</subject><subject>Proton-Translocating ATPases - metabolism</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Uncoupling</subject><issn>0014-5793</issn><issn>1873-3468</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><recordid>eNp9kc9u1DAQxi0EKtvCG4DkA0LlkOI_iR33gIQqoJUqcaCcLduZsIbEDnayYh-DN8ZhV3vswbLG85vPM98g9IqSK0qoeE8IratGKn6pyLuWtExUzRO0oa3kFa9F-xRtTshzdJ7zT1LilqozdMaoFIKSDfr7bfDT5MMPPC3jlHFMeEpxjgEPYH5l7AOOf3xnZr8DPG1jLifthxLHcI0ftoCH6MyATYA8b2H2Dttl8jvjjA-AnVkyZJzLJ6uU28_RbVMcS-agmwHHHo9-fY-hS968QM96M2R4ebwv0PfPnx5ubqv7r1_ubj7eV47zZi4TSt5ZarmtVd1JUJKBUjUY2RqpWMcAiLGguJGECyGMZb3lhXS1dJYDv0BvD7pl3t9L6V6PPjsYhjJKXLJuCSNMClbA-gC6FHNO0Osp-dGkvaZEr5vQq816tVkrov9vQjel7PVRf7EjdKeio_Ul_-aYN7k42CcTnM8nrOGNZEwW7MMBg-LFzkPS2XkIDjqfwM26i_7xPv4BXr2oSw</recordid><startdate>19901217</startdate><enddate>19901217</enddate><creator>van Dam, Karel</creator><creator>Shinohara, Yasuo</creator><creator>Unami, Akira</creator><creator>Yoshida, Kenji</creator><creator>Terada, Hiroshi</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19901217</creationdate><title>Slipping pumps or proton leaks in oxidative phosphorylation: The local anesthetic bupivacaine causes slip in cytochrome c oxidase of mitochondria</title><author>van Dam, Karel ; Shinohara, Yasuo ; Unami, Akira ; Yoshida, Kenji ; Terada, Hiroshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c335t-3473db1b3b494d7e972e994ea78a792d2ee0abe93a703666ab2fb34d7c47cb3e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Anilino Naphthalenesulfonates - pharmacology</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Bupivacaine - pharmacology</topic><topic>Cell physiology</topic><topic>Electron Transport Complex IV - metabolism</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hydrogen-Ion Concentration</topic><topic>Local anesthetic</topic><topic>Male</topic><topic>Mitochondria</topic><topic>Mitochondria, Liver - drug effects</topic><topic>Mitochondria, Liver - metabolism</topic><topic>Molecular and cellular biology</topic><topic>Oxidative phosphorylation</topic><topic>Oxidative Phosphorylation - drug effects</topic><topic>Oxygen Consumption - drug effects</topic><topic>Proton pump</topic><topic>Proton-Translocating ATPases - metabolism</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Uncoupling</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van Dam, Karel</creatorcontrib><creatorcontrib>Shinohara, Yasuo</creatorcontrib><creatorcontrib>Unami, Akira</creatorcontrib><creatorcontrib>Yoshida, Kenji</creatorcontrib><creatorcontrib>Terada, Hiroshi</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>FEBS letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van Dam, Karel</au><au>Shinohara, Yasuo</au><au>Unami, Akira</au><au>Yoshida, Kenji</au><au>Terada, Hiroshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Slipping pumps or proton leaks in oxidative phosphorylation: The local anesthetic bupivacaine causes slip in cytochrome c oxidase of mitochondria</atitle><jtitle>FEBS letters</jtitle><addtitle>FEBS Lett</addtitle><date>1990-12-17</date><risdate>1990</risdate><volume>277</volume><issue>1</issue><spage>131</spage><epage>133</epage><pages>131-133</pages><issn>0014-5793</issn><eissn>1873-3468</eissn><coden>FEBLAL</coden><abstract>Evidence is presented to show that the local anesthetic bupivacaine causes slip in the mitochondrial proton pump cytochrome
c oxidase.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>2176610</pmid><doi>10.1016/0014-5793(90)80826-5</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0014-5793 |
| ispartof | FEBS letters, 1990-12, Vol.277 (1), p.131-133 |
| issn | 0014-5793 1873-3468 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80202762 |
| source | ScienceDirect Journals |
| subjects | Anilino Naphthalenesulfonates - pharmacology Animals Biological and medical sciences Bupivacaine - pharmacology Cell physiology Electron Transport Complex IV - metabolism Fundamental and applied biological sciences. Psychology Hydrogen-Ion Concentration Local anesthetic Male Mitochondria Mitochondria, Liver - drug effects Mitochondria, Liver - metabolism Molecular and cellular biology Oxidative phosphorylation Oxidative Phosphorylation - drug effects Oxygen Consumption - drug effects Proton pump Proton-Translocating ATPases - metabolism Rats Rats, Inbred Strains Uncoupling |
| title | Slipping pumps or proton leaks in oxidative phosphorylation: The local anesthetic bupivacaine causes slip in cytochrome c oxidase of mitochondria |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T15%3A29%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Slipping%20pumps%20or%20proton%20leaks%20in%20oxidative%20phosphorylation:%20The%20local%20anesthetic%20bupivacaine%20causes%20slip%20in%20cytochrome%20c%20oxidase%20of%20mitochondria&rft.jtitle=FEBS%20letters&rft.au=van%20Dam,%20Karel&rft.date=1990-12-17&rft.volume=277&rft.issue=1&rft.spage=131&rft.epage=133&rft.pages=131-133&rft.issn=0014-5793&rft.eissn=1873-3468&rft.coden=FEBLAL&rft_id=info:doi/10.1016/0014-5793(90)80826-5&rft_dat=%3Cproquest_cross%3E80202762%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c335t-3473db1b3b494d7e972e994ea78a792d2ee0abe93a703666ab2fb34d7c47cb3e3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=80202762&rft_id=info:pmid/2176610&rfr_iscdi=true |