Glass–Rubber Transitions of Cellulosic Polymers by Dynamic Mechanical Analysis

The glass–rubber transition temperatures (Tg) of several cellulosic polymers [hydroxypropyl methylcellulose (HPMC), hydroxypropyl cellulose (HPC), hydroxyethyl cellulose (HEC)] have been examined using dynamic mechanical analysis (DMA). The melting temperatures of the above polymers were examined us...

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Published in:Journal of pharmaceutical sciences 1990-09, Vol.79 (9), p.845-848
Main Authors: Kararli, Tugrul T., Hurlbut, Jeffrey B., Needham, Thomas E.
Format: Article
Language:English
Subjects:
Applied sciences
Cellulose - analogs & derivatives
Cellulose - chemistry
Cellulose and derivatives
Chemical Phenomena
Chemistry, Physical
Exact sciences and technology
Glass
Hypromellose Derivatives
Methylcellulose - analogs & derivatives
Natural polymers
Physicochemistry of polymers
Polymers - chemistry
Rubber
Temperature
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cited_by cdi_FETCH-LOGICAL-c4572-42ea13ad6a4ee9e5f803219727db71ce85c3d04ce28df2e366a0736749be39c13
cites cdi_FETCH-LOGICAL-c4572-42ea13ad6a4ee9e5f803219727db71ce85c3d04ce28df2e366a0736749be39c13
container_end_page 848
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container_title Journal of pharmaceutical sciences
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creator Kararli, Tugrul T.
Hurlbut, Jeffrey B.
Needham, Thomas E.
description The glass–rubber transition temperatures (Tg) of several cellulosic polymers [hydroxypropyl methylcellulose (HPMC), hydroxypropyl cellulose (HPC), hydroxyethyl cellulose (HEC)] have been examined using dynamic mechanical analysis (DMA). The melting temperatures of the above polymers were examined using a hot stage melting point apparatus. The primary Tg of three different grades of HPMC (3, 6, and 15 cps) were determined to be 160, 170, and 175°C, respectively. The primary Tg of the HEC film was determined as 120°C. The HPC film did not indicate a primary Tg. These cellulosic polymers also displayed secondary transitions. Hot stage melting of HPMC and HPC was observed at 225 to 254°C and 190 to 195°C, respectively. The HEC powder did not exhibit a melting temperature, but became darker at temperatures >150°C.
doi_str_mv 10.1002/jps.2600790922
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The melting temperatures of the above polymers were examined using a hot stage melting point apparatus. The primary Tg of three different grades of HPMC (3, 6, and 15 cps) were determined to be 160, 170, and 175°C, respectively. The primary Tg of the HEC film was determined as 120°C. The HPC film did not indicate a primary Tg. These cellulosic polymers also displayed secondary transitions. Hot stage melting of HPMC and HPC was observed at 225 to 254°C and 190 to 195°C, respectively. 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Pharm. Sci</addtitle><description>The glass–rubber transition temperatures (Tg) of several cellulosic polymers [hydroxypropyl methylcellulose (HPMC), hydroxypropyl cellulose (HPC), hydroxyethyl cellulose (HEC)] have been examined using dynamic mechanical analysis (DMA). The melting temperatures of the above polymers were examined using a hot stage melting point apparatus. The primary Tg of three different grades of HPMC (3, 6, and 15 cps) were determined to be 160, 170, and 175°C, respectively. The primary Tg of the HEC film was determined as 120°C. The HPC film did not indicate a primary Tg. These cellulosic polymers also displayed secondary transitions. Hot stage melting of HPMC and HPC was observed at 225 to 254°C and 190 to 195°C, respectively. 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Pharm. Sci</addtitle><date>1990-09</date><risdate>1990</risdate><volume>79</volume><issue>9</issue><spage>845</spage><epage>848</epage><pages>845-848</pages><issn>0022-3549</issn><eissn>1520-6017</eissn><coden>JPMSAE</coden><abstract>The glass–rubber transition temperatures (Tg) of several cellulosic polymers [hydroxypropyl methylcellulose (HPMC), hydroxypropyl cellulose (HPC), hydroxyethyl cellulose (HEC)] have been examined using dynamic mechanical analysis (DMA). The melting temperatures of the above polymers were examined using a hot stage melting point apparatus. The primary Tg of three different grades of HPMC (3, 6, and 15 cps) were determined to be 160, 170, and 175°C, respectively. The primary Tg of the HEC film was determined as 120°C. The HPC film did not indicate a primary Tg. These cellulosic polymers also displayed secondary transitions. Hot stage melting of HPMC and HPC was observed at 225 to 254°C and 190 to 195°C, respectively. The HEC powder did not exhibit a melting temperature, but became darker at temperatures &gt;150°C.</abstract><cop>Washington</cop><pub>Elsevier Inc</pub><pmid>2273473</pmid><doi>10.1002/jps.2600790922</doi><tpages>4</tpages></addata></record>
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subjects Applied sciences
Cellulose - analogs & derivatives
Cellulose - chemistry
Cellulose and derivatives
Chemical Phenomena
Chemistry, Physical
Exact sciences and technology
Glass
Hypromellose Derivatives
Methylcellulose - analogs & derivatives
Natural polymers
Physicochemistry of polymers
Polymers - chemistry
Rubber
Temperature
title Glass–Rubber Transitions of Cellulosic Polymers by Dynamic Mechanical Analysis
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