Sample Preparation by Ultrafiltration for Direct Gas Chromatographic Analysis of Ethylene Glycol in Plasma

The application of ultrafiltration to sample preparation in the detection and quantification of ethylene glycol in plasma by gas chromatography is described. After addition of the butylene glycol internal standard and ultrafiltration, the sample is directly injected, obviating the need for further d...

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Bibliographic Details
Published in:Journal of analytical toxicology 1982-11, Vol.6 (6), p.324-326
Main Authors: Cummings, Kenneth C., Jatlow, Peter I.
Format: Article
Language:English
Subjects:
Chromatography, Gas
Ethylene Glycols - blood
Humans
Ultrafiltration
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Description
Summary:The application of ultrafiltration to sample preparation in the detection and quantification of ethylene glycol in plasma by gas chromatography is described. After addition of the butylene glycol internal standard and ultrafiltration, the sample is directly injected, obviating the need for further dilution. This simple, efficient method of sample preparation is also suitable for more sensitive gas chromatographic measurement of other volatiles.
ISSN:0146-4760
1945-2403
DOI:10.1093/jat/6.6.324