ANTIBACTERIAL ACTIVITY OF 9 ANTIBIOTICS IN RELATION TO SEROTYPE AND ENZYME PRODUCTION OF PSEUDOMONAS AERUGINOSA

Efficacy of 9 antibiotics against Pseudomonas aeruginosa in relation to serotype and enzyme production was investigated on 68 strains isolated from patients at Hiroshima Prefectural Hiroshima Hospital during a period from November, 1980 through November, 1981. The results are summalized as follows....

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Bibliographic Details
Published in:Japanese journal of antibiotics 1982/12/25, Vol.35(12), pp.2805-2811
Main Authors: TSUKIYAMA, FUMIAKI, KATOH, MASAFUMI, IIDA, TAKASHI, NAKAMURA, KOHJI, WATANABE, TAKASHI, IKEDA, MISAKO, MUROKI, KUNIO, FUJIUE, YOSHIHIRO, KUWABARA, MASAO
Format: Article
Language:Japanese
Subjects:
Anti-Bacterial Agents - pharmacology
Drug Resistance, Microbial
Pancreatic Elastase - biosynthesis
Peptide Hydrolases - biosynthesis
Pseudomonas aeruginosa - classification
Pseudomonas aeruginosa - drug effects
Pseudomonas aeruginosa - enzymology
Serotyping
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Summary:Efficacy of 9 antibiotics against Pseudomonas aeruginosa in relation to serotype and enzyme production was investigated on 68 strains isolated from patients at Hiroshima Prefectural Hiroshima Hospital during a period from November, 1980 through November, 1981. The results are summalized as follows. 1.SISO was the most effective and followed with GM, AMK, CFS, CPM, PIPC, CPZ, CMX and SBPC in the order. 2.Strains obtained from throat swab and sputum were relatively susceptible, while those from urine were resistant in general. 3.As for serotype, strains belonged to type B were more susceptible than those of type E and G to 3 aminoglycosides. 4.No characteristic pattern was observed between enzyme production and susceptibility.
ISSN:0368-2781
2186-5477
DOI:10.11553/antibiotics1968b.35.2805