Hair and plasma zinc levels following exclusion of biliopancreatic secretions from functioning gastrointestinal tract in humans

Pancreatic secretions have been shown to be important in zinc absorption in experimental animals. Recently, complete surgical diversion of biliary and pancreatic secretions from the functioning small intestine has been utilized in Europe to treat morbid obesity. To determine the importance of pancre...

Full description

Saved in:
Bibliographic Details
Published in:Digestive diseases and sciences 1983-04, Vol.28 (4), p.300-305
Main Authors: Vanderhoof, J A, Scopinaro, N, Tuma, D J, Gianetta, E, Civalleri, D, Antonson, D L
Format: Article
Language:English
Subjects:
Adult
Duodenum - surgery
Female
Hair - analysis
Humans
Ileum - surgery
Intestinal Absorption
Jejunum - surgery
Male
Obesity - therapy
Pancreas - metabolism
Pancreas - surgery
Zinc - blood
Zinc - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Pancreatic secretions have been shown to be important in zinc absorption in experimental animals. Recently, complete surgical diversion of biliary and pancreatic secretions from the functioning small intestine has been utilized in Europe to treat morbid obesity. To determine the importance of pancreatic secretions in zinc absorption in the human, we measured hair and serum zinc levels in 14 patients having undergone complete biliopancreatic bypass 12-56 months earlier and compared these values with those obtained from 11 patients subjected to only partial biliopancreatic bypass as well as to six morbidly obese controls. No differences were observed in either hair or serum zinc levels between any of these groups of patients. Pancreatic secretions do not appear to be necessary for adequate zinc absorption in humans.
ISSN:0163-2116
1573-2568
DOI:10.1007/BF01324945