Erythromycin Failure in the Treatment of Syphilis in a Pregnant Woman

A pregnant woman with a history of allergy to penicillin was diagnosed as having primary syphilis. Two successive courses of erythromycin therapy failed to cure the infection. Penicillin desensitization and therapy were initiated and were successful. The newborn was diagnosed as having probable cong...

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Bibliographic Details
Published in:Sexually transmitted diseases 1983-01, Vol.10 (1), p.36-38
Main Authors: HASHISAKI, PETER, WERTZBERGER, GEOFFREY G., CONRAD, GARY L., NICHOLS, CRAIG R.
Format: Article
Language:English
Subjects:
Adult
Erythromycin - analogs & derivatives
Erythromycin - therapeutic use
Erythromycin Ethylsuccinate
Female
Humans
Infant, Newborn
Penicillin G - therapeutic use
Pregnancy
Pregnancy Complications, Infectious - drug therapy
Syphilis - drug therapy
Syphilis, Congenital - drug therapy
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Description
Summary:A pregnant woman with a history of allergy to penicillin was diagnosed as having primary syphilis. Two successive courses of erythromycin therapy failed to cure the infection. Penicillin desensitization and therapy were initiated and were successful. The newborn was diagnosed as having probable congenital syphilis. This case emphasizes the need for close follow-up of pregnant women after erythromycin treatment for early syphilis.
ISSN:0148-5717
1537-4521
DOI:10.1097/00007435-198301000-00008