False-Positive Tc-99m Pentavalent DMSA Uptake in the Imaging of Medullary Carcinoma of the Thyroid

Tc-99m labeled pentavalent DMSA has been shown to be a reliable imaging agent for the detection of both soft tissue and bony metastases in patients with medullary carcinoma of the thyroid. In a recent series, all patients with distant metastases showed abnormal foci Tc-99m pentavalent DMSA uptake, a...

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Bibliographic Details
Published in:Clinical nuclear medicine 1991-02, Vol.16 (2), p.136-137
Main Authors: LETTE, JEAN, MONIER, DANIELLE, LEDOUX, ROGER, LEVASSEUR, ANDRÉ
Format: Article
Language:English
Subjects:
Carcinoma - diagnostic imaging
False Positive Reactions
Humans
Organotechnetium Compounds
Radionuclide Imaging
Succimer
Technetium Tc 99m Dimercaptosuccinic Acid
Thyroid Neoplasms - diagnostic imaging
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Summary:Tc-99m labeled pentavalent DMSA has been shown to be a reliable imaging agent for the detection of both soft tissue and bony metastases in patients with medullary carcinoma of the thyroid. In a recent series, all patients with distant metastases showed abnormal foci Tc-99m pentavalent DMSA uptake, and 95% of lesions were detected. There were no documented cases of false-positive uptake among 56 patients with histologically proven medullary carcinoma of the thyroid reported in three large studies. A patient is described with false-positive uptake of Tc-99m labeled pentavalent DMSA in a molar root fragment with a periapical granuloma.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-199102000-00019